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This Week in AI

Jason Calacanis
This Week in AI
Latest episode

22 episodes

  • This Week in AI

    Are world models the unlock for Physical AI? | Episode 19

    06/25/2026 | 1h 13 mins.
    This Week In Startups is made possible by:
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    Today’s show:
    *When we think of “Physical AI,” most of us conjure images of humanoid robots and self-driving cars. But there’s a lot more to the category than just breakdancing Chinese bots and Waymos, from excavators autonomously digging tomorrows worksites, to a robot the size of four pizza boxes deploying to the ISS.
    Guest host Alex Wilhelm sits down with three founders in the trenches of the Physical AI Space:
    Boris Sofman of Bedrock Robotics, which builds autonomous construction equipment
    Jeff Hawke of Odyssey, a frontier AI lab specializing in world models for robotics and video games
    Ethan Barajas of Icarus Robotics, designers of the free-flying Joy robot that will join the ISS crew in 2027
    Guests:
    Boris Sofman on X: https://x.com/bsofman
    Bedrock Robotics: https://bedrockrobotics.com/
    Jeff Hawke on X: https://x.com/jeffrey_hawke
    Odyssey: https://odyssey.ml/
    Ethan Barajas on X: https://x.com/ethanbarajas11
    Icarus Robotics: https://www.icarusrobotics.com/
    Relevant Links
    Bedrock Excavators Remove 65,000 Cubic Yards of Dirt: https://www.enr.com/articles/61982-bedrock-robotics-excavators-remove-65-000-cubic-yards-of-dirt-on-southwest-project
    Odyssey $310M Series B article: https://techcrunch.com/2026/06/17/world-model-maker-odyssey-nabs-1-45b-valuation-backed-by-amazon-and-other-big-names/
    Icarus “Joyride” Mission announcement: https://thedebrief.org/icarus-is-building-the-robotic-labor-force-for-space-voyager-technologies-is-sending-a-next-generation-zero-gravity-robot-on-a-joyride-to-space/
    PROWL: Prioritized Regret-Driven Optimization for World Model Learning: https://arxiv.org/abs/2605.18803
    NVIDIA Cosmos 3 report: https://research.nvidia.com/labs/cosmos-lab/cosmos3/technical-report.pdf
    ISS Columbus Laboratory Module: https://www.nasa.gov/international-space-station/columbus-laboratory-module/
    NASA’s Astrobee flying robot: https://www.nasa.gov/astrobee/
    Voyager Technologies: https://www.voyagerspace.com/
    Vast Space: https://www.vastspace.com/
    Blue Origin’s New Glenn: https://www.blueorigin.com/new-glenn
    “Red Mars” by Kim Stanley Robinson: https://www.amazon.com/Red-Mars-Stanley-Robinson/dp/0553560735
    “Rendezvous with Rama” by Arthur C. Clarke: https://www.amazon.com/Rendezvous-Rama-Arthur-Clarke/dp/0553287893
    Theo Von “This Past Weekend” podcast: https://www.theovon.com/podcast
    Anthropic statement on Fable/Mythos suspension: https://www.anthropic.com/news/fable-mythos-access
    Timestamps:
    0:00 The Year of Physical AI
    1:28 Why everyone's bullish on world models
    7:03 Physical AI is harder, but probably bigger
    9:08 How to think about world models
    16:00 When data becomes "adversarial"
    25:00 How Bedrock powers autonomous excavators
    30:48 Why teleoperation gets a bad rap
    39:10 Meet Joy the space robot
    41:33 Laser comms coming to next-gen stations
    46:29 Why everyone hates data centers
    57:33 When does Claude Fable come back?
    Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com
    Check out the TWIST500: https://www.twist500.com
    Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp
    Follow Lon:
    X: https://x.com/lons
    Follow Alex:
    X: https://x.com/alex
    LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm
    Follow Jason:
    X: https://twitter.com/Jason
    LinkedIn: https://www.linkedin.com/in/jasoncalacanis
    Check out all our partner offers: https://partners.launch.co/
    Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland
    Check out Jason’s suite of newsletters: https://substack.com/@calacanis
    Follow TWiST:
    Twitter: https://twitter.com/TWiStartups
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    Substack: https://twistartups.substack.com
  • This Week in AI

    Why AI Models Aren’t the Product Any More | TWiAI Ep 18

    06/18/2026 | 1h 21 mins.
    SpaceX bought Cursor for $60 billion. Satya Nadella says companies need to stop relying on third party AI models and build their own “token capital.” The focus is shifting from LLMs to the application layer sitting on top of them. Here to unpack what that means are guest experts Ali Ansari (Micro1) and Ryan Daniels (Crosby).Plus we get a sneak peek at their new contract redlining benchmark, a crucial eval for how well LLMs don’t just answer questions about the law, but demonstrate actual legal reasoning.Timestamps:0:00 SpaceX acquires Cursor7:36 Distillation vs. building your own model19:43 Nadella's "Frontier Without an Ecosystem"30:21 AI in the courtroom32:15 Ando: the intriguing new workplace tool1:05:38 Inside Micro1 and Crosby's new benchmark1:07:14Guests:Ali Ansari: https://x.com/aliansarinikMicro1: https://www.micro1.ai/Ryan Daniels: https://x.com/ryanjdanielsCrosby: https://crosby.ai/Relevant Links:Bloomberg: “SpaceX acquires Cursor for $60B”: https://www.bloomberg.com/news/articles/2026-06-16/spacex-cements-60-billion-deal-to-take-over-ai-startup-cursorQuinn Thompson “brilliant corporate finance” post: https://x.com/qthomp/status/2066859672749977988Business Insider: “Inside Cursor’s Wild Rise”: https://www.businessinsider.com/cursor-ceo-michael-truell-spacex-elon-musk-anthropic-2026-6Satya Nadella: “A frontier without an ecosystem is not stable”: https://x.com/satyanadella/article/2066182223213293753Joshua Browder’s Do Not Pay: https://donotpay.com/Harvard Magazine: “AI Outperforms Doctors in Emergency Room Tasks”: https://www.harvardmagazine.com/ai/ai-outperforms-doctors-diagnosis-harvard-studyJoshua Kushner “Long Humans” post: https://x.com/JoshuaKushner/status/2065093542809092465Ando: https://ando.so/Nim Ravid on X: https://x.com/Nim_Ravid1Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisCheck out all our partner offers: https://partners.launch.co/Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason’s suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.com
  • This Week in AI

    Hermes Agent, NotebookLM & LiveKit Founders on the AI Agent Race | TWiAI 17

    06/10/2026 | 1h 28 mins.
    Apple just paid a rival a billion dollars a year because it could not build Siri itself, and that tells you where the AI platform war actually stands: the edge has moved up the stack, from the model to the agent layer sitting on top of it.

    This week's roundtable makes the case that whoever controls that layer controls the experience, and we brought in three founders building it from different angles: Hermes Agent, NotebookLM, and LiveKit. Their through-line is that the harness is temporary, the model keeps eating it, and the people building agents right now are designing for capabilities that do not exist yet.

    This week's roundtable:
    Jeffrey Quesnelle (Co-founder & CEO, Nous Research, the open source AI lab behind Hermes Agent)
    Steven B Johnson (Editorial Director of NotebookLM & Google Labs, co-creator of NotebookLM)
    Russ d'Sa (Co-founder & CEO, LiveKit, the open source real-time voice/video infrastructure behind ChatGPT voice mode)

    Thank you to our exclusive sponsor: PayPal Open, One Platform for All Business: https://paypalopen.com

    Timestamps:
    0:00 Cold open
    1:08 Welcome to Episode 17
    1:40 Jeffrey Quesnelle on Hermes Agent and the open source agent race
    5:03 Steven Johnson on NotebookLM, source-grounding, and going agentic
    7:32 Why AI got booed at commencement: the first generation raised on ChatGPT
    10:48 Russ d'Sa on LiveKit powering ChatGPT, Tesla, Grok, and Salesforce voice
    27:50 Apple's $1B Gemini deal and the Siri UX problem
    52:49 "Functional AGI, unevenly distributed": where the models actually are
    57:24 The harness is temporary: why agent builders design for the next model

    Guests:
    Jeffrey Quesnelle, Nous Research: https://nousresearch.com | https://x.com/theemozilla
    Steven Johnson, NotebookLM (Google Labs): https://notebooklm.google.com | https://x.com/stevenbjohnson
    Russ d'Sa, LiveKit: https://livekit.io | https://x.com/dsa

    Referenced in this episode:
    Nous Research / Hermes Agent: https://nousresearch.com
    NotebookLM: https://notebooklm.google.com
    LiveKit: https://livekit.io
    OpenAI ChatGPT: https://openai.com
    Tesla: https://www.tesla.com
    Grok (xAI): https://x.ai
    Salesforce Agentforce: https://www.salesforce.com/agentforce
    SAP Joule: https://www.sap.com/products/artificial-intelligence/ai-assistant.html
    Apple Intelligence: https://www.apple.com/apple-intelligence
    Google Gemini: https://gemini.google.com
    Anthropic Claude Code: https://www.anthropic.com/claude-code
    OpenRouter: https://openrouter.ai

    Newsletter and all platforms: https://thisweekinai.ai
    Apple Podcasts: https://thisweekinai.ai/apple
    Spotify: https://thisweekinai.ai/spotify
    YouTube: https://youtube.com/@ThisWeekinAIPodcast
    Show X: https://x.com/ThisWeeknAI

    #ThisWeekInAI #AI #NousResearch #NotebookLM #LiveKit #OpenSourceAI #AIAgents #Siri #Gemini #VoiceAI
  • This Week in AI

    AI Layoffs, Compute Costs & Agents | Naveen Rao & Alex Finn on This Week in AI Episode 16

    06/04/2026 | 54 mins.
    The future of AI isn't about whether the model is smart enough. It's about whether we can afford to run it. We dug into the AI cost panic, the energy wall that's coming for compute, and why "developers are disappearing" gets the economics exactly backwards.This week's roundtable: Naveen Rao (CEO of Unconventional AI, building brain-inspired analog chips, formerly sold companies to Intel and Databricks) and Alex Finn (founder of Henry Intelligent Machines and Creator Buddy).Thank you to our exclusive sponsor: PayPal Open, One Platform for All Business: http://paypalopen.com/Timestamps:0:00 Cold open1:21 Welcome to Episode 162:44 Is the AI cost panic real, or just "token maxing"?5:08 It's not the intelligence, it's how people use AI9:40 Surgeons vs. shotguns: prompt discipline & matching models to tasks13:10 Naveen's path from Intel and Databricks to Unconventional15:08 Why developers aren't disappearing18:37 How energy overtook CapEx in the cost of compute21:34 The energy wall & getting to 3 orders of magnitude more efficient25:52 AI's PR problem & the data center backlash27:55 China's hunger vs. America's AI boogeyman30:38 Data center taxes, equity stakes & the politics of AI upside37:54 The Anthropic IPO & how these founders actually invest🔗 Guests:Naveen Rao, Unconventional AI: https://unconv.ai | https://x.com/AlexFinnAlex Finn, Henry Intelligent Machines: https://meethenry.ai | https://x.com/NaveenGRao🔗 Host:Alex Wilhelm, This Week in Startups: https://x.com/alex🔗 Referenced in this episode:Unconventional AI (analog chips for AI): https://unconv.aiMosaicML (acquired by Databricks): https://www.databricks.com/research/m...Nervana Systems (acquired by Intel)Creator Buddy: https://creatorbuddy.ioQwen (open-weight model Alex runs locally): https://qwenlm.aiNVIDIA DGX Spark: https://www.nvidia.com/en-us/products...Anthropic (filed to go public): https://www.anthropic.comHenry Intelligent Machines: https://meethenry.ai/🔗 Subscribe and follow:Newsletter and all platforms: https://thisweekinai.ai#ThisWeekInAI #AI #UnconventionalAI #NaveenRao #AlexFinn #AnalogComputing #AIcompute #AIenergy #TokenMaxing #AIlayoffs #AnthropicIPO
  • This Week in AI

    "Nobody Lost Their Job to AI, Just the Promise of AI" - This Week in AI Ep 15

    05/27/2026 | 1h 7 mins.
    The AI jobs panic is here. Meta cut 8,000. Intuit cut 3,000. CapEx went up. Nobody can agree if anyone has actually lost a job to AI, or just to the promise of it. We dug into the GPU squeeze, the new craft of "reward engineering," Pope Leo's call to disarm AI, and why Chinese open-source models just blew past American ones in token usage.
    This week's roundtable: Erik Bernhardsson (CEO of Modal Labs, the serverless GPU cloud), Tanay Kothari (CEO of Wispr Flow, the voice dictation app every VC in the valley uses), and Richard Socher (CEO of Recursive Superintelligence and You.com).

    Thank you to our exclusive sponsor:
    PayPal Open, One Platform for All Business: http://paypalopen.com/

    Timestamps:
    0:00 Cold open
    0:53 Welcome to Episode 15
    5:53 Recursive's plan to build a self-improving "Eureka machine"
    8:10 Token spend now exceeds headcount at the frontier
    9:56 GPU crunch, Hopper prices, and the Anthropic-Colossus shockwave
    12:23 Wispr Flow's 90% gross margin playbook
    14:30 Running $100M in marketing with two humans and a swarm of agents
    18:29 Reward hacking, paperclips, and the rise of the "reward engineer"
    24:39 Why CEOs put one person in charge: multi-objective AI
    28:17 Meta's 8,000 layoffs, $145B CapEx, Goldman vs. Stanford
    33:23 "Nobody lost their job to AI, just the promise of AI"
    37:57 Jevons paradox: software demand is infinite, illustrations aren't
    39:48 Meta's keystroke monitoring and the back-channel reaction
    42:55 Equity, Trump accounts, and rooting for your old employer
    44:06 The Bloomberg/Indeed dev jobs chart
    47:34 Jason's pitch: hiring a 22-year-old AI-native "software valet"
    50:29 Pope Leo: "AI needs to be disarmed"
    57:41 Chris Olah on AI displacement and the global poor
    1:00:46 Chinese models hit 9 trillion tokens, DeepSeek V4 Flash goes #1
    1:03:04 Strange biases, Tiananmen Square, and the US open-source vacuum
    1:05:07 Who they're hiring

    🔗 Guests:
    Erik Bernhardsson, Modal Labs: https://modal.com | https://x.com/bernhardsson
    Tanay Kothari, Wispr Flow: https://wisprflow.ai | https://x.com/tankots
    Richard Socher, Recursive Superintelligence / You.com: https://recursive.com | https://x.com/RichardSocher

    🔗 Referenced in this episode:
    Modal Labs: https://modal.com
    Wispr Flow: https://wisprflow.ai
    Recursive Superintelligence launch: https://recursive.com
    You.com: https://you.com
    Anthropic / SpaceX Colossus 1 compute deal: https://www.anthropic.com/news/anthropic-spacex
    TechCrunch on the $1.25B/month Anthropic-xAI compute deal: https://techcrunch.com/2026/05/20/anthropic-will-pay-xai-1-25-billion-per-month-for-compute/
    Meta's 8,000 layoffs and 2026 AI CapEx of $145B: https://www.reuters.com
    Intuit cuts 3,000 jobs to fund AI integration: https://www.reuters.com
    Goldman Sachs CEO David Solomon NYT op-ed on AI job loss: https://www.nytimes.com
    Stanford study on entry-level AI-exposed jobs (-16%): https://digitaleconomy.stanford.edu
    Pope Leo XIV: "AI needs to be disarmed": https://www.vatican.va
    Chris Olah (Anthropic) on AI and the global poor: https://www.anthropic.com
    OpenRouter token usage leaderboard: https://openrouter.ai/rankings
    DeepSeek V4 Flash: https://www.deepseek.com
    Qwen 3 Max (Alibaba): https://qwenlm.ai

    🔗 Subscribe and follow:
    Newsletter and all platforms: https://thisweekinai.ai

    #ThisWeekInAI #AI #ModalLabs #WisprFlow #Recursive #YouCom #DeepSeek #Qwen #MetaLayoffs #Anthropic #Colossus #PopeLeo #RewardHacking #AIJobs #OpenSource
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About This Week in AI
An experts-only AI podcast: Think the 'All In' podcast for AI. Jason + 3 CEO-level experts breaking down the news & trends.
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