PodcastsHealth & WellnessPeptide of The Week

Peptide of The Week

JD Denham and Will Haas
Peptide of The Week
Latest episode

93 episodes

  • Peptide of The Week

    Peptide Q&A #40 - Traveling With Peptides, Tirzepatide vs. Retatrutide & Bacteriostatic Water Facts

    05/07/2026 | 1h 4 mins.
    Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

    Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas cover bacteriostatic water shelf life, traveling with peptides, fixing chronic injuries, why Clenbuterol is outdated, and when to switch from Tirzepatide to Retatrutide.

    Chapters:
    00:00 – Intro & Parenting Talk
    07:59 – Warrior Makers Meetup & School Update
    10:06 – Bacteriostatic Water & AOD Discussion
    15:28 – PNC-27, Cancer & Fasting
    21:06 – Back Injury, Wolverine & Healing
    26:10 – Loose Skin, GHK-CU & Fat Loss
    30:43 – Traveling with Peptides & Retatrutide
    38:26 – Sleep, Brain Fog & Recovery
    43:26 – TRT, HGH & Fat Loss Stack
    47:48 – Anavar, Clenbuterol & Cutting
    52:15 – HGH, Tesa & Long-Term Protocols
    56:32 – Tendonitis, Recovery & Wolverine Dosing
    1:00:47 – Weight Loss Plateau & Retatrutide

    We cover:
    • Bacteriostatic Water — The Real 28-Day Rule: What actually happens after 28 days and why bottle size affects your timeline
    • AOD-9604 After 13 Weeks: Why it's time to rotate and what SLU-PP-332 and 5-Amino-1-MQ can replace it with
    • PNC-27 for Cancer Prevention: What the science says and why fasting may still be the smarter proactive move
    • Back Injury at Night, Fine During Day: When BPC + TB-500 help vs. when it's a structural issue requiring higher doses
    • Loose Skin After Major Fat Loss: Why GHK-CU beats Snap-8 for collagen remodeling and why HGH is the real game changer
    • Traveling With Peptides: Check your bag, use a peptide case, travel unmixed, and why syringes cause more headaches than peptides
    • Switching From Tirzepatide to Retatrutide: Why poor appetite is a side effect not a goal and why you don't need to wait 14 days
    • Sleep Protocol That Actually Worked: Magnesium glycinate, glycine, ashwagandha, time-release melatonin and Epithalon for circadian reset
    • Anavar vs. Clenbuterol: Why Clen is largely outdated and why high-dose SLU-PP-332 or Retatrutide does it cleaner
    • HGH Plus Tesamorelin — Does It Make Sense?: Why Tessa still burns belly fat even when HGH suppresses pituitary signaling
    • Chronic Heel Tendonitis Protocol: Why two years of injury needs a heavy loading blast and why rest matters just as much

    📌 Subscribe for weekly, no-fluff protocols, dosing guidance, and real-world results.

    You're a warrior. Act like one.

    Follow us on social media:
    JD's Instagram: https://www.instagram.com/jd_denham_fit
    Will's Instagram: https://www.instagram.com/williamthaas/
    Join The Community: https://www.skool.com/peptideresearchinstitute/about
  • Peptide of The Week

    Peptide of the Week: Hair Restoration & Longevity Medicine – With Dr. Sam Borghei & Todd Padberg

    05/04/2026 | 57 mins.
    Medical Disclaimer: We are not doctors. This content is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

    Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas are joined by Dr. Sam Borghei 20-year ER physician and owner of My Hair MD and Todd Padberg, General Manager of My Hair MD. We dig into hair restoration, natural-looking results, peptides for recovery, and the future of medicine.

    Chapters:
    00:00 – Intro & Guest Introduction03:18 – ER Life, Stress & Burnout06:14 – Personality Traits of ER Doctors10:08 – Transition Out of ER12:16 – Hair Transplant Process Explained18:04 – Procedure, Recovery & Limitations23:02 – Industry Trends & Patient Demand25:55 – Recovery, Peptides & Healing29:41 – Cost Breakdown & Expectations34:23 – Preventative Medicine & Telehealth Vision38:57 – Trust in Medicine Post-COVID43:12 – Peptides, Research & Future Outlook49:00 – Fitness, Hormones & Lifestyle54:54 – Contact Info & Outro

    We cover:
    🧬 Who is Sam Borghei? 20+ years in frontline ER medicine. Now owner of My Hair MD in San Diego and building a telehealth longevity platform focused on hormone optimization, weight loss, and personalized wellness.

    ✂️ How a hair transplant works FUE method: follicles are individually extracted from the DHT-resistant donor zone (back of the head). A 3,000–3,500 graft procedure involves 10,500+ steps over 6–8 hours. Grafts are sorted by size heavy grafts go to the back, singles go up front for a natural hairline. Those donor follicles do NOT grow back you have a finite supply (6,000–10,000 max).

    🎨 The art of a natural result Hairlines are drawn jagged on purpose. Single hairs line the very front, temples are always filled in, and age-appropriate design matters. Artistry makes all the difference.

    💉 Peptides & hair recovery Will used BPC-157, TB-500, and GHK-Cu shampoo post-transplant. BPC-157 and TB-500 support angiogenesis and blood flow to follicles. GHK-Cu supports collagen production and scalp stabilization. Will's results were fast with minimal shedding. PRP and laser light therapy are also available at My Hair MD.

    💊 Medications that protect your transplant Dutasteride blocks DHT (which miniaturizes and kills follicles). Minoxidil increases blood flow to support graft survival. Both are commonly used alongside transplants.

    💡 Pricing FUE: ~$3.50/graft | FUT strip: ~$3.00/graft. All-inclusive, no hidden fees, financing available. Online consultations offered. Contact Todd: [email protected]

    🩺 Where medicine is heading Dr. Borghei's telehealth platform (Summer) offers personalized longevity plans biomarker monitoring, hormone optimization, weight loss, and hair restoration. His take: medicine is not one-size-fits-all, and the patient-physician relationship needs to come back.

    🧠 Real talk on peptides Peptides are chains of amino acids with a remarkably low risk profile compared to many pharmaceuticals. FDA classifications are shifting, research is coming, and early adopters are already seeing results.

    Follow for more:
    My Hair MD: myhairmd.com | [email protected] 
    JD's IG: @jd_denham_fit | 
    Will's IG: @williamthaas | 
    Community: skool.com/peptideresearchinstitute
  • Peptide of The Week

    Peptide Q&A #39 – The Full GH Peptide Breakdown, IGF-1 LR3 Protocols, with Paul Bakhtiar

    04/30/2026 | 1h 22 mins.
    Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

    Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas sit down with returning guest Paul Bakhtiar president of telehealth for one of the largest peptide manufacturers in the country and keynote speaker at major peptide conferences for a deep dive into the entire growth hormone peptide category, IGF-1 LR3 protocols, how to stack without overlapping pathways, male fertility, and much more.

    Chapters:
    00:00 – Intro to Peptides & Telehealth
    06:01 – Growth Hormone Overview
    11:50 – Timing & Dosing Peptides
    18:04 – AOD 9604 & Fat Loss
    25:55 – Optimizing GH & Bloodwork
    30:23 – GH Peptides Breakdown (Tesa, CJC, Sermorelin)
    35:40 – Peptide Blends & Side Effects
    44:29 – HGH Risks, Legality & Hormones
    51:21 – Slu-PP-332 & Fat Loss
    54:11 – Fasting, Cancer & Healing (BPC-157)
    1:01:41 – NAD+, Protocols & Final Takeaways

    We cover:
    • Mixing Multiple Peptides in One Syringe: Why it's safe, how to do it right, and why you don't need to be a pin cushion
    • The Full GH Peptide Hierarchy Explained: HGH vs. secretagogues vs. IGF-1 LR3 — what replaces, stimulates, and bypasses your natural growth hormone and when to use each
    • IGF-1 LR3 Timing, Dosing & Cycle Length: Pre- vs. post-workout debate, why 20–40 mcg is the sweet spot, and why four to six weeks on with equal time off is the smart approach
    • Tesamorelin vs. Sermorelin vs. CJC-1295: Strength rankings, dosing protocols, pituitary vs. blood plasma signaling, and why Tessa is Paul's top pick
    • Ipamorelin Ratios for Women: Why equal blends can cause water retention and the case for keeping Ipa lower relative to Tessa or CJC
    • IGF-1 Sweet Spot on Blood Work: Why 250–350 is the optimal range for fat loss, lean muscle, sleep quality, and cognitive function
    • AOD-9604 & SLU-PP-332 Fat Loss Protocols: Proper AOD dosing, fasted cardio timing, and what the latest sloop studies show at higher milligram doses
    • SS-31 Then MOTS-C for Mitochondrial Health: How to sequence them, the loading and maintenance phase for metabolic damage, and managing histamine reactions
    • NAD+ Dosing Done Right — and What Happens When You Overdo It: Why 200mg per week is the sweet spot and what happens when you accidentally take 500mg
    • Optimal Blood Work Markers for Testosterone: Total, free, DHEA, and SHBG targets for men and women — and why DHEA is a $25 fix most people overlook
    • Male Fertility Protocol: HCG dosing, HMG every other day, N-clomiphene citrate, and why Paul avoids standard clomid
    • BPC-157, Angiogenesis & Cancer Research: What the latest rat model studies show about wound healing vs. chaotic angiogenesis and why the risk conversation is shifting

    📌 Subscribe for weekly, no-fluff protocols, dosing guidance, and real-world results.

    You're a warrior. Act like one.

    Follow Paul Bakhtiar:
    Instagram: https://www.instagram.com/paulbakhtiar/
    His Links: https://thepeptidepro.co/linktree

    Follow us on social media:
    JD's Instagram: https://www.instagram.com/jd_denham_fit
    Will's Instagram: https://www.instagram.com/williamthaas/
    Join The Community: https://www.skool.com/peptideresearchinstitute/about
  • Peptide of The Week

    Peptide of the Week: NAD+ & Tesofensine: Anti-Aging and Brain-Based Weight Loss Explained

    04/27/2026 | 58 mins.
    Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

    Welcome back, warriors! JD Denham and William T. Haas break down two powerhouse compounds NAD+ and Tesofensine covering what they are, how they work, real-world experience, and how to dose them right.

    Chapters:
    00:00 – Intro & Life Updates
    05:30 – Parenting, Discipline & Boys
    10:00 – Family, Values & Growth
    18:30 – NAD Explained (What It Does)
    25:30 – NAD Benefits & Real Results
    29:00 – NAD Dosing & Side Effects
    37:45 – NAD Cycles & Best Use
    38:15 – Tesofensine Breakdown
    42:00 – Energy, Focus & Fat Loss Effects
    48:30 – Who Should (and Shouldn’t) Use It
    52:30 – Dosing, Side Effects & Warnings
    55:30 – School Platform & What’s Next
    57:45 – Outro

    🧬 What is NAD+? A coenzyme found in every cell in your body — essential for life. Powers over 500 enzymatic reactions and is critical for ATP (cellular energy) production. Declines dramatically with age: 100% at birth → 55% by age 40 → 34% by age 60. That decline is why we age — cells stop repairing and regenerating as well.

    🔥 What NAD+ actually does – DNA and cellular repair — slows aging at the genetic level – Boosts natural cellular energy (not stimulant energy) – Neuroprotective — mental clarity, sharper focus, better brain function – Improves insulin sensitivity, lipid regulation, and cardiovascular function – Regulates inflammatory pathways and immune response

    🧠 What is Tesofensine? A triple reuptake inhibitor (serotonin + dopamine + norepinephrine). Originally developed for Alzheimer's and Parkinson's — researchers noticed patients losing massive amounts of weight. Clinical trials showed 9–11% average body weight loss over 24 weeks.

    ⚖️ How Tesofensine works – Targets the brain — makes food stop giving you a dopamine hit – Reduces cravings for sweets and junk without fully suppressing hunger like GLP-1s – Does NOT spike blood sugar during fasting – Real energy increase — dopamine-driven motivation, not jittery stimulant energy – Great GLP-1 transition compound for weaning off without falling off track

    💡 Real-world experience JD's first run felt off and tired — gave it a bad rep initially. Second run (last 3 weeks): loves the focused, clean energy, similar to Modafinil. Will: no more naps, more motivated, doesn't want to miss the day. Both agree — take it in the first half of the day, it will keep you up.

    ⚠️ What to avoid – Do NOT combine with SSRIs, SNRIs, or NDRIs (Zoloft, Wellbutrin, etc.) – Reduce caffeine — unnecessary stimulant overload – Do NOT combine with Modafinil – Not recommended for uncontrolled hypertension, bipolar disorder, or severe anxiety – Monitor blood pressure and run regular bloodwork

    📺 Subscribe for more no-fluff peptide education every week.
    Follow us on social media:
    JD's Instagram: https://www.instagram.com/jd_denham_fit
    Will's Instagram: https://www.instagram.com/williamthaas/
    Join The Community: https://www.skool.com/peptideoftheweekcommunity/about
  • Peptide of The Week

    Peptide Q&A #38 – Peptide Testing & Quality Control, HGH for Women & Post-Menopause Weight Loss

    04/23/2026 | 1h 18 mins.
    Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

    Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas break down why peptide companies skip advanced testing, how to stack IGF-1 LR3 without overdoing growth pathways, HGH safety for women post-menopause, fixing dangerously low testosterone at 28, and when to pull back Retatrutide and start TRT.

    Chapters:
    00:00 – Intro & Podcast Catch-Up
    11:13 – Peptide Testing & Quality Concerns
    20:16 – IGF-1, HGH & Stack Overlap
    29:20 – Women’s Hormones & Hysterectomy
    32:15 – Menopause, Weight Gain & Peptides
    44:16 – Peptide Storage & Shelf Life
    49:44 – NAD+ Crystallization Explained
    51:37 – Growth Hormones for Women (Age 44)
    59:44 – Low Testosterone & Mental Health (Age 28)
    1:05:48 – Building Muscle Without Steroids (Athlete Q&A)

    We cover:
    • Why Peptide Companies Don't Test for Endotoxins & Heavy Metals: The real cost breakdown, why cheap peptides come with trade-offs, and how quality standards are rising
    • Kisspeptin on TRT — Why It Won't Work: How TRT shuts down the signal kisspeptin needs and why HCG is the smarter choice for testicular health on cycle
    • IGF-1 LR3 Stacking Rules: Why combining HGH, secretagogues, and IGF-1 all at once is too much on the same pathway — and how to rotate smarter
    • Peptide Shelf Life & Storage Explained: Bacteriostatic vs. sterile water, why HGH is especially sensitive, and the practical rule of thumb for reconstituted peptides
    • What Causes NAD+ to Crystallize: Dilution ratios, the importance of amber vials, and how to troubleshoot this common issue
    • Kisspeptin After Hysterectomy: Why it likely won't work without the ovaries and why direct hormone replacement is the better path forward
    • HGH Safety for Post-Menopausal Women: Addressing 50 pounds of menopause weight gain, why 1 IU of HGH beats secretagogues at this stage, and peptides that target brain fog, mood, skin, and libido
    • CJC vs. Tesamorelin for Women with Water Retention: Why switching to Tessa and adding AOD is the cleaner approach when CJC causes uncomfortable fluid retention
    • Low Testosterone at 28 — Fix That First: Why 315 total and 15 free testosterone explains SSRIs, brain fog, depression, and low energy better than anything else
    • Building Lean Muscle for a Rugby Athlete Without Steroids: Why SLU-PP-332, Cardarine, creatine, and smart fasting are the right tools at 26
    • BPC-157 Subcutaneous vs. Local Injection for Back Injuries: Why abdominal sub-q still works systemically and how BPC + TB-500 rebuild connective tissue post-dislocation
    • When to Start TRT & HGH Mid Weight Loss Journey: Why 51 with 35 pounds already lost is the perfect time — and how to wean Retatrutide down the right way

    📌 Subscribe for weekly, no-fluff protocols, dosing guidance, and real-world results.

    You're a warrior. Act like one.

    Follow us on social media:
    JD's Instagram: https://www.instagram.com/jd_denham_fit
    Will's Instagram: https://www.instagram.com/williamthaas/
    Join The Community: https://www.skool.com/peptideoftheweekcommunity/about

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About Peptide of The Week

Hosted by JD Denham and Will Haas, The Peptide of The Week Podcastis your no-BS guide to peptides, performance, and total body optimization. Whether you’re an athlete, a high performer, or just hungry to feel better, move better, and live stronger this show’s for you. JD and Will dive deep into real-world protocols, hard-earned lessons, and the science behind what actually works. With expert guests and raw conversations, you’ll get everything from cutting-edge peptide talk to diet, training, recovery, and mindset. No fluff. No filters. Just the tools to rebuild your body and upgrade your life.
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