Diabetes Care "On Air"

• Kenneth Cusi on metabolic dysfunction-associated steatotic liver disease, Guido Freckmann and Stefan Pleus on glycemic metrics derived from CGMs, and more!

  Kenneth Cusi on metabolic dysfunction-associated steatotic liver disease, Guido Freckmann and Stefan Pleus on glycemic metrics derived from CGMs, and more! Welcome to episode no. 34 (July 2025) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the July 2025 issue of Diabetes Care and beyond. 1:05 Mike and Alice mark the 75th anniversary of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). During this period, the organization has contributed to innumerable discoveries that have improved the health of millions of Americans, especially those with diabetes. For more, visit diabetesjournals.org/collection/2745/NIDDK-75th-Anniversary-Collection. 3:35 Alice is joined by Kenneth Cusi, MD, endocrinologist and Professor of Medicine at University of Florida in Gainesville, Florida. They discuss his consensus report, “Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD) in People With Diabetes: The Need for Screening and Early Intervention. A Consensus Report of the American Diabetes Association,” available for free at doi.org/10.2337/dci24-0094. 29:15 Mike speaks with Guido Freckmann, MD, Director of the Institute for Diabetes Technology at the University of Ulm in Germany, and Stefan Pleus, current Chair of the International Federation of Clinical Chemistry and Laboratory Medicine working group on CGMs. They discuss their article, “A Comparative Analysis of Glycemic Metrics Derived From Three Continuous Glucose Monitoring Systems,” available for free at doi.org/10.2337/dc25-0129. 42:35 In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the July 2025 issue of Diabetes Care. Studies highlighted in this segment include: Abdul-Ghani et al. One-Hour Plasma Glucose Predicts the Progression From Normal Glucose Tolerance to Prediabetes doi.org/10.2337/dc24-2832 Kuo et al. Cost-effectiveness of the National Diabetes Prevention Program: A Real-world, 2-Year Prospective Study doi.org/10.2337/dc24-1110 Murthy et al. Human Physiologic Responses to Insulin in Indigenous Americans Identify a Metabolic Susceptibility Profile Linked to Diabetes doi.org/10.2337/dc25-0151 Li et al. Alcohol Intake, Drinking Pattern, and Risk of Type 2 Diabetes in Three Prospective Cohorts of U.S. Women and Men doi.org/10.2337/dc24-1902 Kohler et al. Trends in Cystic Fibrosis–Related Diabetes Epidemiology Between 2003 and 2018 From the U.S. Cystic Fibrosis Foundation Patient Registry doi.org/10.2337/dc25-0044 Sun et al. Metformin Use and Risk of Delirium in Older Adults With Type 2 Diabetes doi.org/10.2337/dc24-1414 To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.

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• Deborah Wexler on weight gain associations in the GRADE Randomized Controlled Trial, Justin Echouffo-Tcheugui on the success—or lack of success—of the lifestyle modification approach to preventing T2D, and more!

  Welcome to episode no. 33 (June 2025) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the June 2025 issue of Diabetes Care and beyond. 6:50 Alice is joined by past guest Deborah Wexler, MD, MSC, chief of the Massachusetts General Hospital Diabetes Unit, and Associate Professor of Medicine at Harvard Medical School. They discuss her article, “Weight Gain Was Associated With Worsening Glycemia and Cardiovascular and Kidney Outcomes in Patients With Type 2 Diabetes Independent of Diabetes Medication in the GRADE Randomized Controlled Trial,” available for free at doi.org/10.2337/dc24-2825. 18:40 Mike speaks with Justin Echouffo-Tcheugui, MD, PhD, Associate Professor of Medicine in the Division of Endocrinology at Johns Hopkins School of Medicine. They address the core question in his article, “Is the Current Lifestyle Modification Approach to Diabetes Prevention in the U.S. a Success?” available for free at doi.org/10.2337/dci24-0040. 43:20 In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the May 2025 issue of Diabetes Care. Studies highlighted in this segment include: Bapat et al. Capillary Ketone Level and Future Ketoacidosis Risk in Patients With Type 1 Diabetes Using Sodium–Glucose Cotransporter Inhibitors doi.org/10.2337/dc25-0125 Pitta et al. Empagliflozin in Type 2 Diabetes Undergoing On-Pump CABG: The POST-CABGDM Randomized Clinical Trial doi.org/10.2337/dc24-2807 Retnakaran et al. 1-hour Oral Glucose Tolerance Test for the Postpartum Reclassification of Women with Hyperglycemia in Pregnancy doi.org/10.2337/dc24-1848 Ginzberg et al. Islet Autoantibodies and Their Association with β Cell Function and Diabetes Measures in Children with Acute Recurrent and Chronic Pancreatitis doi.org/10.2337/dc24-2672 Smedegaard et al. Pre-Meal Whey Protein Lowers Postprandial Blood Glucose in Women with Gestational Diabetes Mellitus – A Randomized, Crossover Clinical Trial. doi.org/10.2337/dc24-2831 Perrier et al. Impact of Islet Transplantation on Diabetic Complications and Mortality in Patients Living with Type 1 Diabetes doi.org/10.2337/dc25-0059 To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.

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• The art of Diabetes Care, Geremia Bolli on the modern role of basal insulin in advancing T2D therapy, Michael Bowen on the derivation and validation of D-RISK, and more!

  Welcome to episode no. 32 (May 2025) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the May 2025 issue of Diabetes Care! and beyond. 2:30 Alice is joined by John Buse, MD, PhD, endocrinologist and Director of the Diabetes Care Center at the University of North Carolina Chapel Hill (UNC), and Mary Beth Cassely, MSPH, Director of the Innovation Program team at UNC. Husband and wife, they’re also the photographers behind the May issue cover art. Their profile is available for free at diabetesjournals.org/care/article/48/5/669/158168/About-the-Artists-John-B-Buse-MD-PhD-and-Mary-Beth. 14:45 Mike speaks with Geremia B Bolli, MD, an endocrinologist at the University of Perugia, in Italy, and first author of the article, “The Modern Role of Basal Insulin in Advancing Therapy in People With Type 2 Diabetes,” available for free at https://doi.org/10.2337/dci24-0104. 26:25 Discussing a feature article, “Derivation and Validation of D-RISK: An Electronic Health Record–Driven Risk Score to Detect Undiagnosed Dysglycemia in Clinical Practice,” Alice is joined by lead author Michael E. Bowen, MD. Dr. Bowen is Associate Professor in the Department of Internal Medicine, the Department of Population and Data Sciences, and the Department of Pediatrics at UT Southwestern Medical Center in Dallas, Texas. This article is available for free at doi.org/10.2337/dc24-1624. 52:35 In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the May 2025 issue of Diabetes Care. Studies highlighted in this segment include: Rickels et al. Islet Transplantation Versus Standard of Care for Type 1 Diabetes Complicated by Severe Hypoglycemia From the Collaborative Islet Transplant Registry and the T1D Exchange Registry doi.org/10.2337/dc24-1915 Zhao et al. Association Between Use of Sodium–Glucose Cotransporter 2 Inhibitors and Epilepsy: A Population-Based Study Using Target Trial Emulation doi.org/10.2337/dc24-2532 Boonpattharatthiti et al. Comparison of Insulin Titration Strategies for Glycemic Control in Type 2 Diabetes: A Systematic Review and Network Meta-analysis doi.org/10.2337/dc24-2661 Wang et al. Association Between Diabetes and Anemia: Evidence From NHANES and the UK Biobank doi.org/10.2337/dc24-2535 Ostrominski et al. Efficacy and Safety of Finerenone in Type 2 Diabetes: A Pooled Analysis of Trials of Heart Failure and Chronic Kidney Disease doi.org/10.2337/dc24-1873 Thierry et al. Short-term Metformin Protects Against Glucocorticoid-Induced Toxicity in Healthy Individuals: A Randomized, Double-Blind, Placebo-Controlled Trial doi.org/10.2337/dc24-2039 To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.

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• Managing hyperglycemia in the hospital, glycemic impact of protein ingestion in T1D, and more!

  Welcome to episode no. 31 (April 2025) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the April 2025 issue of Diabetes Care and beyond. Our hosts begin by highlighting some fun facts about April. Of note: it’s Defeat Diabetes Month! This campaign aims to raise awareness around issues of diabetes prevention and management. 2:07 Mike is joined by Linnea M. Wilson, Clinical Research Coordinator at the Beth Israel Deaconess Medical Institution in Boston and Timothy S. Anderson, MD, MAS, Assistant Professor of Medicine at the Center for Research on Health Care at the University of Pittsburgh in Pennsylvania. They discuss their article, “Management of Diabetes and Hyperglycemia in the Hospital: A Systematic Review of Clinical Practice Guidelines,” available for free at doi.org/10.2337/dc24-2510. 15:00 Alice speaks with Dale J. Morrison, PhD, an exercise physiologist and research fellow at the University of Melbourne as part of the Diabetes Technology Research Group. His Perspectives in Care article, “The Glycemic Impact of Protein Ingestion in People With Type 1 Diabetes,” is available for free at doi.org/10.2337/dci24-0096. 38:40 In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the April 2025 issue of Diabetes Care. Studies highlighted in this segment include: Cromie et al. Diabetes Risk After Treatment for Childhood and Young Adult Cancer doi.org/10.2337/dc24-2171 Wentworth et al. Islet Autoantibody Screening Throughout Australia Using In-Home Blood Spot Sampling: 2-Year Outcomes of Type1Screen doi.org/10.2337/dc24-2443 Kang et al. Longitudinal Associations of PFAS Exposure With Insulin Sensitivity and β-Cell Function Among Hispanic Women With a History of Gestational Diabetes Mellitus doi.org/10.2337/dc24-2056 Desouter et al. Repeated OGTT Versus Continuous Glucose Monitoring for Predicting Development of Stage 3 Type 1 Diabetes: A Longitudinal Analysis doi.org/10.2337/dc24-2376 Lau et al. Development and Validation of the Patient-Level Chinese Diabetes Outcome Model on Long-term Complications in Type 2 Diabetes: An Application of the Hong Kong Diabetes Register doi.org/10.2337/dca24-0069 Olsen et al. In-Hospital Diabetes Management by a Diabetes Team and Insulin Titration Algorithms Based on Continuous Glucose Monitoring or Point-of-Care Glucose Testing in Patients With Type 2 Diabetes (DIATEC): A Randomized Controlled Trial doi.org/10.2337/dc24-2222 To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.

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• Financial interventions for diabetes care, glucagon-like peptide 1 receptor agonist outcomes for asian & white populations, and more!

  Welcome to episode no. 30 (March 2025) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the March 2025 issue of Diabetes Care and beyond. To mark the month of Ramadan, our hosts begin by highlighting a series of practical resources to help people with diabetes minimize risk while religious fasting. These resources include Section 5 of the 2025 Standards of Care, as well as guidelines provided by the Diabetes and Ramadan International Alliance. 2:45 Mike is joined by Leonard E. Egeda, MD, MS, FACP, the Charles and Mary Bauer Professor of Medicine and Chair of the Department of Medicine at the University at Buffalo Jacobs School of Medicine and Biomedical Sciences in Buffalo, New York. They discuss his article, “Financial Incentives, Income Supplementation, Cash Transfer, and Universal Basic Income Interventions in Diabetes: Understanding Differences and Effectiveness: A Scoping Review,” available for free at doi.org/10.2337/dci24-0072. 15:30 Alice speaks with Matthew Lee, PhD, Cardiology Senior Lecture and Honorary Clinical Lecturer at the University of Glasgow, and Naveed Sattar, PhD, Professor of Cardiometabolic Medicine and Honorary Consultant at the University of Glasgow. Their meta-analysis, “Comparative Efficacy of Glucagon-Like Peptide 1 Receptor Agonists for Cardiovascular Outcomes in Asian Versus White Populations: Systematic Review and Meta-analysis of Randomized Trials of Populations With or Without Type 2 Diabetes and/or Overweight or Obesity,” is available for free at https://doi.org/10.2337/dc24-1533. 28:40 In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the March 2025 issue of Diabetes Care. Studies highlighted in this segment include: Bardenheier et al. Prevalence of Diagnosed Diabetes Among U.S. Adults Aged ≥18 Years With Disabilities, 2021–2022 doi.org/10.2337/dci24-0086 Xu et al. Incidence and Risk Factors of Diagnosed Young-Adult-Onset Type 2 Diabetes in the U.S.: The National Health Interview Survey 2016–2022 doi.org/10.2337/dc24-1699 Griffin et al. Use of SGLT2i Versus DPP-4i as an Add-on Therapy and the Risk of PAD-Related Surgical Events (Amputation, Stent Placement, or Vascular Surgery): A Cohort Study in Veterans With Diabetes doi.org/10.2337/dc24-1546 Osmulski et al. Subtypes of Gestational Diabetes Mellitus Are Differentially Associated With Newborn and Childhood Metabolic Outcomes doi.org/10.2337/dc24-1735 Hirsch et al. A Randomized Trial Comparing Inhaled Insulin Plus Basal Insulin Versus Usual Care in Adults With Type 1 Diabetes doi.org/10.2337/dc24-1832 Barovic et al. Proteomic and Metabolomic Signatures in Prediabetes Progressing to Diabetes or Reversing to Normoglycemia Within 1 Year doi.org/10.2337/dc24-1412 To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.

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