Hello Hormones with Dr. Carrie Jones

Why does heart disease suddenly become such a big issue for women after perimenopause?
In this episode, I sit down with Dr. Eve Henry, a physician specializing in longevity and women's health, to talk through how heart and metabolic health often shift quickly in midlife, even when nothing about your lifestyle has changed.
We cover how estrogen loss impacts cholesterol, blood pressure, and blood sugar, and which markers matter most, including ApoB and A1C. We also talk about visceral fat and inflammation, how they affect long-term heart health, and where hormone therapy, lifestyle support, and early intervention fit in.
Dr. Eve Henry is a board-certified internal medicine physician with advanced training in integrative medicine, and she's deeply focused on helping women protect their heart and metabolic health through midlife and beyond.
What's Discussed:
(00:00) Why heart disease is the leading health risk for women

(05:52) Why cholesterol is often the first lab to change in perimenopause

(06:43) How estrogen loss changes cholesterol and blood pressure 

(14:22) Blood sugar changes, inflammation, and visceral fat in midlife

(19:04) Perimenopause as a metabolic stress test

(23:41) ApoB, Lp(a), A1C and baseline labs women should know

(40:37) Coronary calcium scans vs CT angiograms

(57:21) Why early intervention matters for long-term heart health

 
✍️ FREE GUIDES:
Hormones 101 Cheat Sheet:  https://drcarriejones.kit.com/hormones101 

The Perimenopause & Menopause Labs Test Checklist: https://drcarriejones.kit.com/labtestchecklist

The Symptoms of The Perimenopausal Transition (WTF…) Ebook: https://drcarriejones.kit.com/perimenopausesymptom 

Which Stage of Perimenopause Am I In? Ebook: https://drcarriejones.kit.com/stagesofperimenopause 

 
LETS CONNECT: 
Dr. Carrie Jones:
Website: www.drcarriejones.com
Newsletter: www.drcarriejones.kit.com/newsletter
Instagram: @dr.carriejones
Facebook: @drcarriejones
TikTok: @drcarriejones
Youtube: @drcarriejones
Pinterest: @drcarriejones 
Dr. Eve Henry:
Website: www.drevehenry.com
Instagram: @drevehenry
X: @DrEveHenry1
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Disclaimer: Information provided on this channel is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided on this channel for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided on this channel and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Carrie Jones. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.

Hormone therapy gets confusing fast, especially when you're over 40 and everyone seems to have a different rule, warning or opinion. 
Many of the most common questions about it come from gaps in how it's explained. When nuance is missing, women are left trying to make decisions without the full picture.
In this Hello Hormones episode, I'm gonna pick the nine questions I hear all the time and go over them one by one with you. We talk about progesterone versus progestins, patch myths, vaginal hormone options and what actually matters when it comes to blood pressure and HRT. Tune in.
What's Discussed:
(01:26) The difference between progesterone and progestins 

(03:06) About Prometrium, peanut allergies and safer progesterone options

(05:15) Why topical progesterone doesn't protect the uterus when using estrogen

(09:11) Which estrogen patches are true estradiol and which contain progestins

(11:09) Vaginal estrogen vs vaginal DHEA and when each one makes sense

(15:06) What actually matters about blood pressure when considering HRT

✍️ FREE GUIDES:
Hormones 101 Cheat Sheet:  https://drcarriejones.kit.com/hormones101 

The Perimenopause & Menopause Labs Test Checklist: https://drcarriejones.kit.com/labtestchecklist

The Symptoms of The Perimenopausal Transition (WTF…) Ebook: https://drcarriejones.kit.com/perimenopausesymptom 

Which Stage of Perimenopause Am I In? Ebook: https://drcarriejones.kit.com/stagesofperimenopause 

 
LETS CONNECT: 
Dr. Carrie Jones:
Website: www.drcarriejones.com
Newsletter: www.drcarriejones.kit.com/newsletter
Instagram: @dr.carriejones
Facebook: @drcarriejones
TikTok: @drcarriejones
Youtube: @drcarriejones
Pinterest: @drcarriejones
==========
Disclaimer: Information provided on this channel is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided on this channel for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided on this channel and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Carrie Jones. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.

Many women hit a weight plateau in perimenopause and assume it's about willpower, when the real issue is that the body isn't getting the physiological support it needs during hormonal change. After 40, eating less and pushing harder often puts the body into a protective mode, signaling it to conserve energy by storing fat.
We dive deeper into this in the latest Hello Hormones episode with Ashley Koff, RD. We also chat about why fasting often backfires in perimenopause, what actually changes when GLP-1 signaling lasts days instead of minutes, and why gut function, hydration, and stress signals decide whether the body feels safe enough to lose weight.
Ashley Koff, RD, is the founder of The Better Nutrition Program and the author of Your Best Shot: The Personalized System for Optimal Weight Health. She is a registered dietitian with over 30 years of experience across private practice, nutrition education, media, and consulting, and serves as Nutrition Course Director for IFMF.
What's Discussed:
(02:59) How under-eating and over-exercising backfire after 40

(03:21) GLP-1 as hormone replacement and why duration matters more than dose

(11:17) Fasting in perimenopause: when it helps and when it hurts

(19:32) Food variety, taste receptors, and GLP-1 signaling on the tongue

(24:26) Stress, the vagus nerve, and why weight gain can be protective

(29:29) The GLP-1 era, weight bias, and why judging bodies misses the point

(43:19) What GLP-1 actually does in the body beyond appetite suppression

(50:37) Can you stimulate GLP-1 naturally and what actually influences it

✍️ FREE GUIDES:
Hormones 101 Cheat Sheet:  www.drcarriejones.kit.com/hormones101 

The Perimenopause & Menopause Labs Test Checklist: www.drcarriejones.kit.com/labtestchecklist

The Symptoms of The Perimenopausal Transition (WTF…) Ebook: www.drcarriejones.kit.com/perimenopausesymptom 

Which Stage of Perimenopause Am I In? Ebook: www.drcarriejones.kit.com/stagesofperimenopause 

 
LETS CONNECT:  
Dr. Carrie Jones:
Website: www.drcarriejones.com
Newsletter: www.drcarriejones.kit.com/newsletter
IG: @dr.carriejones 
TikTok: @drcarriejones
Youtube: @drcarriejones 
Ashley Koff, RD:
Website: www.thebetternutritionprogram.com
Instagram: @ashleykoffapproved
Ashley's Upcoming Book: ORDER HERE
 
Disclaimer: Information provided on this channel is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided on this channel for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided on this channel and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Carrie Jones. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.

If you've been doom-scrolling hormone headlines lately, you probably saw the panic around the FDA removing the boxed warning from vaginal estrogen.
In this episode, we unpack what actually changed and why low-dose vaginal estrogen never belonged in the same risk category as systemic hormones. I walk you through the real differences between vaginal, transdermal, and oral estrogen and why your bloodstream cares a lot about the how, not just the what.
We also look at the research on blood clots and breast cancer without the scary headlines. You'll hear why a tiny vaginal tablet is basically the quiet introvert of hormone therapy, how transdermal estrogen behaves differently once it hits your skin, and why your daily habits can shift these risks more than most people realize.
If you've been wondering what's safe, what's shifting, and what all of this FDA chatter really means for your midlife hormones, this episode will leave you with clarity instead of confusion. Come listen.
What's Discussed:
(03:11) Why removing the boxed warning from vaginal estrogen actually makes sense

(04:22) How low dose vaginal estrogen stays local instead of acting systemically

(08:24) How the route of estrogen use changes clot risk

(09:27) Why transdermal estrogen behaves differently than oral

(12:17) What the research really shows about breast cancer risk

(14:47) How lifestyle factors shift risk as much as hormone choice





✍️ FREE GUIDES:
Hormones 101 Cheat Sheet:  https://drcarriejones.kit.com/hormones101 

The Perimenopause & Menopause Labs Test Checklist: https://drcarriejones.kit.com/labtestchecklist

The Symptoms of The Perimenopausal Transition (WTF…) Ebook: https://drcarriejones.kit.com/perimenopausesymptom 

Which Stage of Perimenopause Am I In? Ebook: https://drcarriejones.kit.com/stagesofperimenopause 

 
LETS CONNECT: 
Dr. Carrie Jones:
Website: www.drcarriejones.com
Newsletter: www.drcarriejones.kit.com/newsletter
Instagram: @dr.carriejones
Facebook: @drcarriejones
TikTok: @drcarriejones
Youtube: @drcarriejones
Pinterest: @drcarriejones
==========
Disclaimer: Information provided on this channel is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided on this channel for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided on this channel and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Carrie Jones. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.

Have you ever wondered why your body reacts so strongly to stress on days that should feel completely normal? 
In this episode, we're joined by naturopathic doctor and educator Dr. Leah Hollon to explore how early stress, family patterns, and even the pregnancies we grew in can shape our hormones decades later. We talk about cortisol patterns, histamine overload, immune shifts, stubborn weight changes, and why so many women hit perimenopause already running a nervous system that's been on high alert for years.
And yes, we get practical. Think nervous system resets, smart cortisol support, histamine-calming strategies, and the small daily practices that genuinely start to retrain your stress response.
Dr. Leah Hollon is a naturopathic doctor, international speaker, and author of Unwinding the Imprints of Disease. She teaches integrative medicine, pharmacogenomics, and epigenetics at multiple universities and co-owns Richmond Natural Medicine. 
It's a grounded, eye-opening look at how stress imprints show up in midlife hormones and what you can do to shift the system starting today. 
 
What's Discussed:
(02:00) What intergenerational trauma is and how it affects hormones

(08:09) How PTSD flattens cortisol and shows up in perimenopause

(11:46) The link between ACEs and autoimmunity, allergies, and migraines

(15:24) What famine studies teach us about metabolism and weight

(17:49) Why chronic stress makes weight loss harder and cardio tricky

(20:23) How your birth story shapes stress, immunity, and hormone patterns

(39:36) Why histamine flares, sleep issues, and wired-tired energy connect

(41:22) Tools that regulate the nervous system and support midlife hormones

 
Thank You To Our Sponsor: 
Timeline Nutrition: If you're feeling tired, foggy, or drained during perimenopause, Timeline's Mitopure Gummies support your energy from the inside out. Powered by clinically proven Urolithin A, they help your cells clean out damaged mitochondria and build new, stronger ones. If you'd like to give it a try, visit timeline.com/drcarrie and get 20% off.

LVLUP Health: If you're in perimenopause, menopause, or just feel like your digestion and hormones are ganging up on you, try Ultimate GI Repair from LVLUP Health. You can grab it at lvluphealth.com and use my code DRJONES for 15% off your first order.

 
✍️ FREE GUIDES:
Hormones 101 Cheat Sheet:  https://drcarriejones.kit.com/hormones101 

The Perimenopause & Menopause Labs Test Checklist: https://drcarriejones.kit.com/labtestchecklist

The Symptoms of The Perimenopausal Transition (WTF…) Ebook: https://drcarriejones.kit.com/perimenopausesymptom 

Which Stage of Perimenopause Am I In? Ebook: https://drcarriejones.kit.com/stagesofperimenopause 

 
LETS CONNECT: 
Dr. Carrie Jones:
Website: www.drcarriejones.com
Newsletter: www.drcarriejones.kit.com/newsletter
IG: @dr.carriejones 
TikTok: @drcarriejones
Youtube: @drcarriejones 
Dr. Leah Hollon, ND, MPH:
Website: www.drleahhollon.com
IG: @leah.hollon
Youtube: @DrLeahHollon
==========
Disclaimer: Information provided on this channel is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided on this channel for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided on this channel and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Carrie Jones. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.