Fat Science

Why is your fat talking to you?
In the latest solo episode, Dr. Emily Cooper, Andrea Taylor, and Mark Wright explore groundbreaking research into metabolic health. Learn why the scale doesn't always reflect metabolic risk, and discover the science behind fat's active role in the body.
 KEY TAKEAWAYS
Metabolic dysfunction cannot be judged by scale weight alone.

Visceral fat is a stronger predictor of heart failure than BMI.

Hormonal environments profoundly affect fat storage and health risks.

NOTABLE QUOTE
"Your fat is talking to you." — Andrea Taylor
LINKS & RESOURCES
Obesity Reviews Paper
Immunological Reviews Journal Article
European Congress on Obesity Study
 Links & Resources
Podcast Home: fatsciencepodcast.com
Cooper Center for Metabolism: coopermetabolic.com
Resources from Dr. Cooper: coopermetabolic.com/resources
Join Our Community: patreon.com/cw/FatSciencePodcast
Submit Your Question: questions@fatsciencepodcast.com or dr.c@fatsciencepodcast.com
Fat Science is supported by the Diabesity Institute, a nonprofit dedicated to increasing access to effective, science-based metabolic care.
This podcast is for informational purposes only and is not intended as medical advice. Please consult with a qualified healthcare provider for personalized recommendations.

Is your brain starving for glucose?
In this episode, Dr. Emily Cooper explores the critical role of the brain as a metabolic organ and its dependence on glucose and insulin. Listeners will learn why good sleep and a holistic lifestyle are vital for cognitive health.
KEY TAKEAWAYS
The brain uses about 20% of your body's energy at rest.

Insulin plays a non-fuel role in brain function, supporting neural connections and mood.

Sleep is essential for the brain's waste clearance system, the glymphatic system.

Insulin resistance in the brain is linked to cognitive decline and dementia.

Exercise, a balanced diet, and social engagement are key to brain health.

NOTABLE QUOTE
"The brain is the most metabolically active organ in our body." — Dr. Emily Cooper
LINKS & RESOURCES
JAMA: US POINTER Study on Cognitive Decline
Novo Nordisk: EVOKE & EVOKE Plus Trials
Links & Resources
Podcast Home: fatsciencepodcast.com
Cooper Center for Metabolism: coopermetabolic.com
Resources from Dr. Cooper: coopermetabolic.com/resources
Join Our Community: patreon.com/cw/FatSciencePodcast
Submit Your Question: questions@fatsciencepodcast.com or dr.c@fatsciencepodcast.com
Fat Science is supported by the Diabesity Institute, a nonprofit dedicated to increasing access to effective, science-based metabolic care.
This podcast is for informational purposes only and is not intended as medical advice. Please consult with a qualified healthcare provider for personalized recommendations.

Is it normal for GLP-1 medications to become less effective over time?
Dr. Emily Cooper discusses listener questions about the nuances of metabolic health and the real reasons behind weight fluctuations and food cravings. With insights into GLP-1 medications, mechanical eating, and more, the episode aims to debunk myths and provide science-based encouragement.
KEY TAKEAWAYS
Trusting your body's hunger signals can prevent metabolic slowdown.

Mechanical eating can help manage sugar cravings and maintain metabolic health.

Navigating pediatric metabolic issues requires understanding genetic influences and appropriate medical intervention.

NOTABLE QUOTE
"It's not your fault. Trust your body and step up to the higher end of your metabolic flexibility." — Dr. Emily Cooper
 
LINKS & RESOURCES
American Board of Obesity Medicine: obesitymedicine.org
 
Links & Resources
Podcast Home: fatsciencepodcast.com
Cooper Center for Metabolism: coopermetabolic.com
Resources from Dr. Cooper: coopermetabolic.com/resources
Join Our Community: patreon.com/cw/FatSciencePodcast
Submit Your Question: questions@fatsciencepodcast.com or dr.c@fatsciencepodcast.com
Fat Science is supported by the Diabesity Institute, a nonprofit dedicated to increasing access to effective, science-based metabolic care.
This podcast is for informational purposes only and is not intended as medical advice. Please consult with a qualified healthcare provider for personalized recommendations.

Have you ever wondered why your body holds onto weight despite your best efforts?
In this eye-opening episode, Dr. Cooper reveals groundbreaking research showing that 100% of healthy adults carry at least six different plastic-related chemicals in their bodies daily. These endocrine disruptors don't just affect your hormones - they may be stored in your fat tissue and could be a hidden driver of metabolic dysfunction. The good news? New Australian research proves you can dramatically reduce these chemicals in just one week with targeted changes.
KEY TAKEAWAYS
Every single person tested had at least 6 plastic chemicals in their urine, with food packaging being the primary source

Participants cut phthalate levels by 38-54% and BPA by 60% in just 7 days with adjustments in reducing plastic exposure in food and food packaging

Ultra-processed foods introduce plastic chemicals through multiple processing and packaging steps

Certain chemicals like DEHP may be stored in fat tissue and released during weight loss

Heat accelerates plastic migration into food - avoid microwaving in plastic and pouring hot food into plastic containers

Simple swaps like choosing fresh over canned foods and using glass containers make significant impacts

The EPA research office studying these chemicals was recently eliminated, removing key consumer protections

NOTABLE QUOTE
"People who switched to the low plastic food and kitchenware cut the phthalates excretion by 38 to 54% in one week and they cut their BPA excretion by 60% in one week." — Dr. Emily Cooper
Links & Resources
Podcast Home: fatsciencepodcast.com
Cooper Center for Metabolism: coopermetabolic.com
Resources from Dr. Cooper: coopermetabolic.com/resources
Join Our Community: patreon.com/cw/FatSciencePodcast
Submit Your Question: questions@fatsciencepodcast.com or dr.c@fatsciencepodcast.com
Fat Science is supported by the Diabesity Institute, a nonprofit dedicated to increasing access to effective, science-based metabolic care.
This podcast is for informational purposes only and is not intended as medical advice. Please consult with a qualified healthcare provider for personalized recommendations.

What happens when GLP-1 medications stop working the way you hoped they would? In this mailbag episode, Dr. Emily Cooper answers listener questions about fasting, insulin levels, PCOS, lipedema, plateaus on Zepbound, and the complicated reality behind metabolic dysfunction. From the dangers of under-fueling to why individualized treatment matters so much, this conversation unpacks the science behind weight resistance with clarity and compassion.Key Takeaways
Why fasting and restrictive eating may worsen metabolic adaptation

The real role insulin plays in metabolic health

How PCOS and lipedema complicate weight loss treatment

Why some people plateau on GLP-1 medications over time

The importance of fueling, muscle preservation, and individualized care

Links & Resources
Podcast Home: fatsciencepodcast.com
Cooper Center for Metabolism: coopermetabolic.com
Resources from Dr. Cooper: coopermetabolic.com/resources
Join Our Community: patreon.com/cw/FatSciencePodcast
Submit Your Question: questions@fatsciencepodcast.com or dr.c@fatsciencepodcast.com
Fat Science is supported by the Diabesity Institute, a nonprofit dedicated to increasing access to effective, science-based metabolic care.
This podcast is for informational purposes only and is not intended as medical advice. Please consult with a qualified healthcare provider for personalized recommendations.