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The VPZD Show

Drs. Vinay Prasad & Zubin Damania
The VPZD Show
Latest episode

41 episodes

  • The VPZD Show

    Pancreatic Cancer Drug, USPSTF, Tylenol-Autism

    09/11/2026 | 1h 42 mins.
    We're trying to become better listeners, SO PREPARE FOR SOME SHOUTING 🤭 Originally streamed ⁠LIVE on YouTube⁠! (#41)

    We cover the new pancreatic cancer drug daraxonrasib and its rash side effect, survival benefit, and cost; what makes pancreatic cancer especially deadly; Vinay’s clinical background across hematology and oncology; how mechanistically cancer actually kills; the challenge of finding good podcast guests and why authenticity matters more than plugging a product; vaccine mandates and the difference between individual versus population-level benefit; the USPSTF’s recent upheaval and the challenge of evidence-based guidelines on contested topics like depression screening, mammograms, and prostate cancer screening; observational versus randomized evidence, with examples spanning flu vaccines, shingles vaccines and dementia, and Tylenol in pregnancy and autism; the OpenAI Navier-Stokes controversy and AI’s role in mathematics; AI in medicine and a JAMA perspective piece on AI replacing physicians; statins, coronary calcium scores, and personal decision-making around cardiovascular risk; weight stigma in medical training and the complexity of obesity; alternative medicine, longevity influencers, and Vinay’s evolving views on certainty; the ethics and mechanics of prediction markets and biotech stock betting; and reflections on active listening and communication style on the show.

    ⁠⁠Dr. Prasad's "Plenary Session" podcast.⁠⁠

    ⁠⁠Dr. Damania's "ZDoggMD Show" podcast.⁠⁠

    ⁠⁠More on Vinay.⁠⁠

    ⁠⁠More on Zubin.

    Learn more about your ad choices. Visit megaphone.fm/adchoices
  • The VPZD Show

    Fauci's Diary, Vinay's FDA Experience, Jason Arday (Recorded LIVE)

    09/10/2026 | 2h 8 mins.
    Yeah it's been over a year but you can't keep a couple of handsome brown guys apart forever 😎 A BRAND NEW VPZD EPISODE, originally streamed LIVE on YouTube! (#40)

    ⁠Dr. Prasad's "Plenary Session" podcast.⁠

    ⁠Dr. Damania's "ZDoggMD Show" podcast.⁠

    ⁠More on Vinay.⁠

    ⁠More on Zubin.

    Learn more about your ad choices. Visit megaphone.fm/adchoices
  • The VPZD Show

    Ivy Leagues, Vaccine Science, Politics & Stuff

    04/23/2025 | 1h
    We're back, just cuz we had dinner and felt like a live nightcap. Enjoy!

    Watch the originally live YouTube video here.

    Subscribe to "The VPZD Show" on your favorite podcast app.

    Dr. Prasad's "Plenary Session" podcast.

    Dr. Damania's "ZDoggMD Show" podcast.

    More on Vinay.

    More on Zubin.

    Learn more about your ad choices. Visit megaphone.fm/adchoices
  • The VPZD Show

    Trump Transition, Reproductive Rights, Vaccine Truth

    11/14/2024 | 1h 24 mins.
    Another live episode, we touch on a BUNCH of stuff, including Trump's transition, possible FDA appointments, RFK Jr., letters we've gotten about reproductive rights, was Harris or her team afraid to have her go on Rogan, a deep dive into COVID infection fatality rate and what to do about vaccines, and MUCH more. Watch the video version here.

    Subscribe to The VPZD Show on your favorite podcast app. Check out VP's Substack Vinay Prasad's Observations and Thoughts as well as Sensible Medicine. Here's all our previous episodes together.

    More on Vinay.
    More on Zubin.
    Learn more about your ad choices. Visit megaphone.fm/adchoices
  • The VPZD Show

    Why Trump Won & What It Means For Healthcare

    11/09/2024 | 1h 38 mins.
    Regardless of your political leanings, this live podcast WILL traumatize you 😻. 
    Election reactions, media polarization, what this might mean for healthcare and WAY more than you cared to hear about Peyronie’s disease 🍆🤓. Watch the video version here.

    Subscribe to The VPZD Show on your favorite podcast app. Check out VP's Substack Vinay Prasad's Observations and Thoughts as well as Sensible Medicine. Here's all our previous episodes together.

    More on Vinay.
    More on Zubin.
    Learn more about your ad choices. Visit megaphone.fm/adchoices
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About The VPZD Show
Two doctors, one podcast, Alt-Middle as heck. Featuring Dr. Vinay Prasad (host of Plenary Session) and Dr. Zubin Damania (host of The ZDoggMD Show).
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