The Dr. Layne Norton Podcast

• Ultra-Processed Foods with Dr. Samuel Dicken

  Ultra-processed foods (UPFs) get a lot of negative press, but are they always as bad as people think? In this episode, I sit down with researcher Samuel Dicken, who recently led a high-profile randomized controlled trial on UPFs that challenged some long-held assumptions.We dig into what his study found, why not all UPFs are created equal, and how the way we consume them might matter more than the processing label itself. At the same time, we explore why sticking with mostly minimally processed foods is still a sound piece of nutrition advice.If you’ve ever wondered whether “ultra-processed” automatically means “unhealthy,” or how to make sense of the latest UPF research, you won’t want to miss this conversation.SPONSORS• David Protein - Buy 4 cartons, get 1 FREE at: https://davidprotein.com/pages/layne• Carbon Diet Coach – 14 day free trial: https://joincarbon.com/podcastLAYNE'S COMPANIESCarbon Diet Coach: https://joincarbon.com/podcastOutwork Nutrition: https://outworknutrition.comREPS Research Review: https://biolayne.com/repsWorkout Builder: https://biolayne.com/workout-builderTeam Biolayne: https://biolayne.com/online-coachingPhysique Coaching Academy: https://physiquecoachingacademy.comFOLLOW LAYNEhttp://www.facebook.com/laynenortonhttp://www.twitter.com/biolaynehttp://www.instagram.com/biolayneFOLLOW SAMhttps://www.instagram.com/drsamueldickenhttp://www.twitter.com/SamuelDickenUKTIMESTAMPS0:00:00 - Intro0:02:16 - Study Design0:12:07 - Study Results0:14:03 - NOVA Food Classification0:18:53 - Research Misinterpretations0:21:04 - Food Choices0:24:34 - Zero Calorie Beverages0:31:40 - Coke HFCS vs Cane Sugar0:34:07 - David Protein0:35:42 - Unintended Consequences0:43:55 - LDL Cholesterol0:47:50 - Ultra-Processed Foods Good or Bad?0:53:11 - Are Ultra-Processed Foods Addictive?1:02:10 - Carbon Diet Coach1:03:10 - Nuance of Ultra-Processed Foods1:07:35 - Negative Effects of UPFs Independent of Calories1:13:09 - Criticism of Study Design1:16:48 - Government Regulation1:23:58 - Behavior Changes1:29:37 - Animal vs Plant Based1:33:08 - Personal Diet Habits1:35:16 - Use Cases For UPFs1:38:33 - The Practical Realities of Research1:45:24 - What Have You Changed Your Mind On1:49:14 - PhD Discussion1:52:42 - OutroSHOW NOTES

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• Study Deep Dive: Creatine is SAFE

  Creatine is SAFE, the verdict is in!After decades of people claiming that creatine will wreck your kidneys, liver, & various other claims, a new study has put these myths to bed. In my latest episode of the Dr. Layne Norton Podcast, I go DEEP on the most comprehensive dataset to date: a brand new meta-analysis by Kreider et al. (2025) which reviewed 250+ studies, covering over 26,000 participants, some lasting more than a decade, and examined nearly 50 potential side effects.The verdict? Absolutely no evidence of harm.I broke down the full paper, the methods, and what this means for athletes and everyday lifters in the latest episode of the podcast.SPONSORS• Outwork Nutrition - Evidence-Based Supplements to Support Your Hard Work: https://outworknutrition.com• REPS Research Review: https://biolayne.com/repsLAYNE'S COMPANIESCarbon Diet Coach: https://joincarbon.com/podcastOutwork Nutrition: https://outworknutrition.comREPS Research Review: https://biolayne.com/repsWorkout Builder: https://biolayne.com/workout-builderTeam Biolayne: https://biolayne.com/online-coachingPhysique Coaching Academy: https://physiquecoachingacademy.comFOLLOW LAYNEhttp://www.facebook.com/laynenortonhttp://www.twitter.com/biolaynehttp://www.instagram.com/biolayneTIMESTAMPS0:00:00 - Intro0:01:33 - Meta Analysis Overview0:02:14 - Creatine is NOT a Steroid0:03:10 - ATP0:05:13 - Creatine from Body and Food0:06:05 - Creatine Non-Responders0:06:27 - Creatine Dose0:07:10 - Creatine Benefits0:10:18 - Outwork Nutrition0:11:46 - Interesting Associations0:13:48 - Safety Questions0:15:03 - Importance of Placebo0:17:05 - Study Methods0:20:05 - Study Results0:26:08 - REPS Research Review0:26:57 - Hair Loss0:29:04 - Creatine is Safe and Effective0:30:54 - Types of Creatine0:36:54 - Creatine for Kids0:38:50 - Recommendations0:39:39 - OutroSHOW NOTEShttps://biolayne.com/podcasts/dr-layne-norton-podcast/study-deep-dive-creatine-is-safe-episode-13

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• Did Sugar Cause The Obesity Epidemic?

  Is sugar really to blame for the obesity epidemic? In this episode, I break down one of the most common nutrition myths. Using evidence from epidemiology, randomized controlled trials, and meta-analyses, Layne explains why sugar and high fructose corn syrup aren’t the independent culprits they’re often made out to be. Instead, he reveals what the research actually says about calories, metabolism, and how oversimplified narratives mislead the public. If you’ve ever been told “sugar is poison,” this episode will challenge your perspective with science, not fear.SPONSORS• REPS Research Review: https://biolayne.com/reps• Carbon Diet Coach – Achieve your goals with Carbon’s adaptive macro coaching app: https://joincarbon.com/podcastLAYNE'S COMPANIESCarbon Diet Coach: https://joincarbon.com/podcastOutwork Nutrition: https://outworknutrition.comREPS Research Review: https://biolayne.com/repsWorkout Builder: https://biolayne.com/workout-builderTeam Biolayne: https://biolayne.com/online-coachingPhysique Coaching Academy: https://physiquecoachingacademy.comFOLLOW LAYNEhttp://www.facebook.com/laynenortonhttp://www.twitter.com/biolaynehttp://www.instagram.com/biolayneTIMESTAMPS0:00:00 - Intro0:02:49 - Research Funding and Bias0:14:52 - Previous Beliefs on Sugar0:15:31 - Types of Sugar0:17:42 - Previous Beliefs on HFCS0:19:37 - Leptin0:23:56 - Gary Taubes0:24:33 - REPS0:25:22 - Carbohydrate Insulin Model of Obesity0:27:42 - The Case for Sugar Causing Obesity0:30:08 - The Moment I Started to Change My Mind0:32:29 - Ice Cream0:34:18 - Researching Sugar0:39:15 - Mechanisms vs Outcomes0:41:10 - Classic Study0:42:28 - Mark Haub Twinkie Diet0:45:46 - Carbon Diet Coach0:46:46 - Metabolic Health0:48:03 - Glycemic Index0:49:51 - Sugar Intake vs Calorie Intake0:52:30 - Sugar Addiction0:54:21 - Let's Be Clear0:56:36 - Data Over FeelingsSHOW NOTEShttps://biolayne.com/podcasts/dr-layne-norton-podcast/did-sugar-cause-the-obesity-epidemic-episode-12

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• Why You Should Try To Build Muscle

  Building muscle isn’t just about aesthetics — it’s about survival. 💪In this episode of The Dr. Layne Norton Podcast, I break down why muscle is the most underrated organ of health. You’ll hear how it lowers your risk of cardiovascular disease, cancer, infections, Alzheimer’s, and depression — while also protecting against falls, fractures, and the effects of aging.We’ll dive into:- How muscle acts like an endocrine organ, releasing myokines that fight disease and slow tumor growth.- Why more muscle means longer life, better quality of life, and faster recovery if you get sick.- The myth that you “can’t build muscle after a certain age” — and why it’s total BS.- How just 50 minutes of resistance training a week can change your health trajectory.If you want to live longer, feel stronger, and age on your own terms, this is the episode you don’t want to skip.SPONSORS• Workout Builder – Customized training programs for all experience levels: https://biolayne.com/workout-builder• Team Biolayne – One-On-One Coaching: https://biolayne.com/online-coachingLAYNE'S COMPANIESCarbon Diet Coach: https://joincarbon.com/podcastOutwork Nutrition: https://outworknutrition.comREPS Research Review: https://biolayne.com/repsWorkout Builder: https://biolayne.com/workout-builderTeam Biolayne: https://biolayne.com/online-coachingPhysique Coaching Academy: https://physiquecoachingacademy.comFOLLOW LAYNEhttp://www.facebook.com/laynenortonhttp://www.twitter.com/biolaynehttp://www.instagram.com/biolayneTIMESTAMPS0:00:00 - Intro0:02:18 - Muscle for Vanity0:03:39 - Cultural Perception of Muscles0:06:13 - Women in the Gym 0:08:11 - Muscle for Health0:10:34 - Sarcopenia0:15:28 - Insulin Sensitivity0:22:59 - Workout Builder0:23:54 - Sink Metaphor0:26:07 - Organ of Health0:28:11 - Quality of Life0:32:35 - Cardiovascular Disease Mortality0:36:35 - Cancer Mortality0:42:44 - Other Mortality0:44:45 - Risk of Disease0:49:22 - Mental Health0:56:19 - Pain & Injuries0:57:35 - Team Biolayne0:58:26 - Wasting Diseases1:00:59 - Anyone Can Build Muscle1:03:20 - OutroSHOW NOTEShttps://biolayne.com/podcasts/dr-layne-norton-podcast/why-you-should-try-to-build-muscle-episode-11

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• How to Build Muscle Masterclass with Professor Brad Schoenfeld

  Learn how to build muscle from the world's most renowned researcher on muscle growth, Professor Brad Schoenfeld. In this absolute masterclass, Dr. Schoenfeld lays out the non-negotiables for muscle growth, what matters most, what matters least, and how to practically implement these recommendations. If you care about building muscle, you do not want to miss this episode.SPONSORS• Workout Builder – Customized training programs for all experience levels: https://biolayne.com/workout-builder• REPS Research Review: https://biolayne.com/repsLAYNE'S COMPANIESCarbon Diet Coach: https://joincarbon.com/podcastOutwork Nutrition: https://outworknutrition.comREPS Research Review: https://biolayne.com/repsWorkout Builder: https://biolayne.com/workout-builderTeam Biolayne: https://biolayne.com/online-coachingPhysique Coaching Academy: https://physiquecoachingacademy.comFOLLOW LAYNEhttp://www.facebook.com/laynenortonhttp://www.twitter.com/biolaynehttp://www.instagram.com/biolayneFOLLOW BRADhttps://www.instagram.com/bradschoenfeldphdhttp://www.twitter.com/bradschoenfeldTIMESTAMPS0:00:00 - Intro0:03:20 - How Brad Got Started0:08:24 - Vanity vs Health0:14:46 - Muscle Quality0:16:54 - Muscle and Insulin Resistance0:22:00 - Most Important Thing for Hypertrophy0:23:38 - Training to Failure0:34:51 - Misinformation on Social Media0:39:02 - Mechanical Tension0:46:21 - Training Volume0:52:24 - Workout Builder0:54:45 - Dose Response0:59:27 - Overtraining1:07:19 - Muscle Damage and Soreness1:14:35 - Mechanisms vs Outcomes1:19:52 - Cortisol1:21:15 - Acute vs Chronic1:24:04 - Mechanisms vs Outcomes1:25:43 - REPS Research Review1:26:32 - Research on Volume1:34:01 - Training Frequency1:40:06 - Range of Motion1:46:27 - Intensity Tricks1:50:32 - Rep Cadence1:58:03 - Exercise Selection2:04:43 - Final Question2:13:53 - OutroSHOW NOTEShttps://biolayne.com/podcasts/dr-layne-norton-podcast/how-to-build-muscle-masterclass-with-professor-brad-schoenfeld-episode-10

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