hol+ by Dr. Taz MD

• What Is Perimenopause Really? The Symptoms No One Warned Women About | Dr. Mariza Snyder

  Millions of women say the same thing in their late 30s and 40s “I don’t feel like myself anymore.” Fatigue grows, stress tolerance collapses, brain fog hits, and everyday tasks suddenly require more effort. Yet most are told it’s “normal aging,” “just stress,” or “anxiety.”In this hol+ episode, Dr. Taz sits down with functional medicine expert and bestselling author Dr. Mariza Snyder to ask the hard questions about perimenopause, what it is, when does perimenopause start, and why rage, irritability, and cognitive changes are often the earliest symptoms women experience.Together, they unpack why perimenopause is widely misdiagnosed, why progesterone decline shows up long before hot flashes or missed periods, how estrogen fluctuations affect brain function, and why so many women feel like their identity, mood, and capacity are suddenly slipping away.From mood swings, brain fog, and sleep crashes to metabolic slowdowns and rising visceral fat, this conversation reframes perimenopause symptoms as hormone-driven neurological and physiological shifts — not personal weakness, aging, or lack of willpower.You will learn what perimenopause is, what age perimenopause starts, why rage and irritability show up first, and how to track early hormone changes through menstrual patterns, symptoms, biometrics, and stress physiology. Dr. Taz and Dr. Mariza also share lifestyle tools, boundaries, morning and evening routines, and targeted support that help stabilize brain energy, mood, and metabolic health during this transition.Dr. Taz and Dr. Mariza discuss: • What is perimenopause and why it hits earlier than women expect • When does perimenopause start and what age perimenopause typically begins • Why perimenopause rage is real and often the first warning sign • Perimenopause brain fog, cognitive shifts, and declining stress tolerance • Progesterone decline, estrogen fluctuations, and why hormones become unpredictable • Perimenopause vs aging: why symptoms are dismissed or misdiagnosed • Mood swings, irritability, fatigue, and the identity shift many women feel • Early metabolic changes in perimenopause and why belly fat increases • How to track symptoms, cycles, HRV, sleep, and biomarkers for early clues • Tools women can use: routines, nervous system regulation, boundaries, lifestyle resets • When progesterone or estrogen support can make a meaningful difference • Why community and sisterhood become critical for emotional resilienceAbout Dr. Mariza Snyder Dr. Mariza Snyder is a functional practitioner, women's health expert, hormone educator, and bestselling author of The Perimenopause Revolution. With over 15 years of clinical experience, she helps women navigate perimenopause and midlife with clarity, confidence, and science-based tools that support hormone balance, brain health, emotional resilience, and metabolic vitality. Her work empowers women to understand what perimenopause is, recognize early symptoms, and take back control of their health with practical strategies and integrative support.Stay Connected:Connect further to Hol+ at https://holplus.co/- Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Follow Dr. Mariza Snyder:Instagram: https://www.instagram.com/drmariza/Podcast: Energized with Dr. Mariza Book: The Perimenopause Revolution Follow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Subscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsGet your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseHost & Production TeamHost: Dr. Taz; Produced by ClipGrowth.com (Producer: Pat Gostek)

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• Gut Health Explained: How Your Gut Microbiome Controls Hormones, Mood and Weight

  Subscribe to the video podcast: https://www.youtube.com/@LiveHolPlus/ Your gut is not just a digestion system, it is one of the most powerful control centers in your body. In this episode, Dr. Taz explains how the gut lining, bile, digestive enzymes, and microbiome all work together to shape your hormones, mood, weight, and inflammation. You will learn why gut health is still not standard of care in conventional medicine, how stress, toxins, sleep, and even popular GLP 1 drugs change the microbiome, and what that means for conditions like anxiety, depression, perimenopause, menopause, and stubborn belly fat.Dr. Taz shares: • Why ancient systems called the gut "ground zero" and modern research is finally catching up • The four pillars of gut health: gut lining, digestive enzymes and stomach acid, bile flow, and a diverse microbiome • How leaky gut, SIBO, candida, and low diversity bacteria drive inflammation, brain fog, rashes, and chronic symptoms • The gut brain axis and why up to 90 percent of serotonin and other neurotransmitters are made in the gut • How butyrate and beta glucuronidase affect estrogen recycling, perimenopause, and andropause, leading to estrogen dominance and hormone shifts • The links between microbiome balance, circadian rhythm, GLP 1 medications, and metabolic syndrome and weight gain • A practical step by step protocol using diet changes, collagen, glutamine, enzymes, probiotics, fermented foods, sleep, and stress tools to rebuild gut healthWhether you are dealing with mood changes, hormone chaos, weight that will not budge, or unexplained symptoms that never fully resolve, this episode gives you a clear roadmap to understand your gut and start rebuilding your microbiome from the inside out.Stay Connected:Connect further to Hol+ at https://holplus.co/- Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Follow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Subscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsGet your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseHost & Production TeamHost: Dr. Taz; Produced by ClipGrowth.com (Producer: Pat Gostek)

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• Nitric Oxide And Your Health: The Root Problem No One Checks | Dr. Nathan Bryan

  Subscribe to the video podcast: https://www.youtube.com/@LiveHolPlus/Cardiovascular disease is still the number one killer, yet guidelines keep pushing cholesterol lower and more people are put on statins for life. In this hol+ episode, Dr. Taz sits down with worlds leading nitric oxide researcher Dr. Nathan S. Bryan to ask hard questions about statin risk versus benefit, why cholesterol alone does not explain heart disease, and what is nitric oxide actually doing inside the body long before a heart attack or stroke. Together, they explore why low or no nitric oxide may be the missing piece behind rising blood pressure, plaque, and dementia, even in people who “follow the rules.”From the benefits of nitric oxide for blood flow, blood pressure, diabetes, and brain health to the surprising impact of antiseptic mouthwash and antacid medications, this conversation reframes cardiovascular and metabolic disease as problems of cell signaling, not just lab numbers. You will learn what nitric oxide is, what does nitric oxide do for the body, why nitric oxide importance is often ignored in standard care, and how to raise nitric oxide through lifestyle, targeted support, and emerging restorative therapies based on decades of nitric oxide research.Dr. Taz and Dr. Bryan discuss:New cholesterol guidelines, statins, and rethinking risk vs benefitWhat is nitric oxide and what does nitric oxide do for the bodyWhy low or no nitric oxide shows up decades before heart attacks and strokeThe benefits of nitric oxide for blood flow, blood pressure, and sexual functionNitric oxide diabetes link and why insulin resistance is often a nitric oxide problemMouthwash and nitric oxide, antacids, fluoride, and the oral microbiomeHow lifestyle, diet, movement, and nasal breathing raise nitric oxide naturallyWhy standard biomarkers are late and vascular function should be tested soonerNitric oxide importance in Alzheimer’s, dementia, and brain blood flowHow to raise nitric oxide safely and what to know about supplements vs “dead beets”About Dr. Nathan S. Bryan Dr. Nathan S. Bryan is a pioneering nitric oxide researcher, molecular medicine scientist, and biotech entrepreneur whose discoveries helped create a billion dollar nitric oxide market. His work has reshaped how we understand cardiovascular disease, metabolic health, nitric oxide diabetes links, and how lifestyle, mouthwash and nitric oxide, and common drugs impact long term health. He is the author of The Secret of Nitric Oxide, where he breaks down what nitric oxide is, what nitric oxide does for the body, and how to raise nitric oxide safely at home using science based tools and lifestyle shifts. Stay Connected:Connect further to Hol+ at https://holplus.co/- Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Follow Dr. Nathan S. Bryan:  YouTube: https://www.youtube.com/@DrNathanSBryanNitricOxideInstagram: https://www.instagram.com/drnathansbryan/ Website: https://www.bryantherapeutics.com/ Product: https://n1o1.com/Get The Secret of Nitric Oxide Book here.Follow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Subscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsGet your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseHost & Production TeamHost: Dr. Taz; Produced by ClipGrowth.com (Producer: Pat Gostek)00:00 New cholesterol rules, statins, and nitric oxide importance01:00 Mouthwash and nitric oxide, blood pressure, and the oral microbiome01:46 What is nitric oxide and what does nitric oxide do for the body03:06 Why nitric oxide matters for longevity, inflammation, and aging cells04:32 Nobel Prize history and early nitric oxide research06:06 Fingerprint of nitric oxide biology and early disease markers08:13 No nitric oxide before you see plaque, blood pressure, or ED09:26 The American lifestyle and nitric oxide diabetes link10:45 Mouthwash and nitric oxide, fluoride, PPIs, and hidden blockers12:26 Statins, cholesterol guidelines, and questioning “everyone needs a statin”16:11 Cholesterol numbers, Framingham data, and what actually predicts risk19:27 Better heart screening, vascular function, and nitric oxide benefits22:28 First symptoms of low nitric oxide: ED, libido, and rising blood pressure25:04 Mouthwash and nitric oxide causation study, exercise benefits lost27:23 Antacids, reflux meds, and how they shut down nitric oxide27:58 How to raise nitric oxide naturally with food, movement, and sunlight30:19 Nasal breathing, mouth breathing, and nitric oxide delivery to the lungs31:02 Nitric oxide as a hormone and whole body signaling molecule33:18 How to measure, how to replace, and what nitric oxide testing really shows36:45 Inflammation, triglycerides, and tracking nitric oxide benefits in labs38:38 Restorative physiology vs applied pharmacology42:01 Can nitric oxide help heart failure, liver disease, and ascites44:13 Nitric oxide diabetes connection and insulin resistance46:52 Nitric oxide and Alzheimer’s, brain blood flow, and “type 3 diabetes”47:57 Kids, ADHD, diet, and low nitric oxide as a blood flow problem49:08 5G, toxins, and electron flow in biochemistry51:00 Glutathione, nitric oxide transport, and why most supplements miss the mark52:18 Why arginine, citrulline, and most beet products do not fix nitric oxide55:40 Nitruticals, rebuilding nitric oxide and the oral microbiome57:32 Nitric oxide for wounds, skin, and regenerative healing59:19 Reversing disease vs managing decline, and what nitric oxide might change1:00:07 Optimizing human performance with nitric oxide as a foundation1:01:18 Where to learn more from Dr. Nathan Bryan1:01:55 Closing thoughts from Dr. Taz and hol+

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• PCOS Without Knowing It? What Is PCOS in Women, How It’s Diagnosed and Why 70 Percent Miss It

  Subscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsWhat Is PCOS in Women, How It’s Diagnosed? PCOS is not just a gynecology label, it is a whole-body syndrome that is widely missed in the exam room. In this episode, Dr. Taz explains why nearly seventy percent of women go undiagnosed, how PCOS often begins in the prenatal environment, and why it behaves like a metabolic and autoimmune condition. You will learn the signs most people overlook, the labs that actually matter, and a step-by-step plan that starts with the gut, supports the liver, balances blood sugar, and calms cortisol so real healing can begin.Dr. Taz shares: • Why the old Rotterdam criteria miss metabolic, inflammatory, and immune drivers • How prenatal hormones, medications, and toxins can program PCOS risk • The role of hyperandrogenism in insulin resistance, inflammation, acne, and hair loss • Why PCOS looks different by life stage and race, and what that means for care • The exact labs to request: DHT, AMH, free and total testosterone, DHEAS, 17-OHP, fasting insulin, lipids, CRP and more • A holistic protocol that begins with gut repair and liver support, then adds androgen and metabolic tools • How daily stress and the cortisol hum keep PCOS active, and practical ways to turn it downWhether you feel off but cannot explain why, are chasing a diagnosis, or want a long term plan for energy, fertility, and hormone balance, this episode gives you a clear roadmap to understand PCOS and take action.Connect further to Hol+ at https://holplus.co/- Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Get your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseStay ConnectedSubscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsFollow Dr. Taz on Instagram:https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Join the conversation on X: https://x.com/@drtazmdTikTok: https://www.tiktok.com/@drtazmdFacebook: https://www.facebook.com/drtazmd/Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+Chapters 00:00 The PCOS epidemic and misdiagnosis 00:27 Dr. Taz’s PCOS story 03:06 Why old criteria fall short 05:09 PCOS as metabolic and autoimmune 08:20 Why PCOS rates are rising 09:14 Prenatal and medication influences 11:05 Childhood and teen clues 15:44 Symptom checklist you can spot 18:42 Eastern medicine patterns to notice 20:32 What to test for PCOS 23:56 How presentation varies by race 30:03 Building a holistic plan 33:37 Gut and liver first 35:16 Androgen, metabolic, and inflammation tools 37:30 Managing cortisol and stress 39:13 Long term roadmap and next steps

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• The Mental Health Crisis No One’s Talking About with Dr. James Greenblatt, MD

  Subscribe to the video podcast: https://www.youtube.com/@LiveHolPlus/podcastsMental health is not a simple checklist, it is a whole body story. In this hol+ episode, Dr. Taz sits down with Dr. James Greenblatt, a pioneer of integrative and nutritional psychiatry, to rethink how we approach depression, anxiety, ADHD, and eating disorders through labs, nutrients, hormones, and personalized care.Together, they unpack why so much suffering persists despite more medications, how root cause testing changes outcomes, and why simple shifts like correcting vitamin D, B12, iron, thyroid, zinc, and omega 3 can transform mood and resilience. They also explore nutrigenomics for precision dosing, the real limits of 10 minute telehealth med checks, and where tools like ketamine, psychedelics, and lithium orotate fit only after foundations are in place.From practical lab targets and cost effective protocols to the crossroads of food, sleep, screens, and ADHD, this conversation invites us to see mental health not as a diagnosis to medicate, but as a system to understand and support.Dr. Taz and Dr. Greenblatt discuss:The gap between symptom focused care and root cause testingKey labs for mood, vitamin D, B12, iron, thyroid, hormonesWhy micronutrients come first for eating disordersMTHFR, methylfolate, glutathione, and antidepressant responseNutrigenomics for personalized vitamin and mineral dosingThe risks of quick med stacking and 10 minute checksWhere ketamine, psychedelics, and lithium orotate may help, and when they do notADHD, ultra processed foods, sugary drinks, sleep, and screen timeAbout Dr. James Greenblatt, MDDr. James Greenblatt, MD is a board certified psychiatrist and a pioneer of integrative and nutritional psychiatry. For more than three decades he has treated patients with ADHD, depression, anxiety, and eating disorders using personalized protocols that combine conventional care with targeted nutrients and lab guided precision. He is the author of multiple books including Finally Focused and the upcoming Finally Hopeful.Connect further to Hol+ at https://holplus.co/- Don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Get your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseStay ConnectedSubscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsFollow Dr. Taz on Instagram:https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Join the conversation on X: https://x.com/@drtazmdTikTok: https://www.tiktok.com/@drtazmdFacebook: https://www.facebook.com/drtazmd/Follow Dr. James Greenblatt MD: Website: https://jamesgreenblattmd.com Platform: https://PsychiatryRedefined.org Instagram: https://instagram.com/psychiatry_redefinedDon’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+00:00 Introduction, testing gap and the B12 tragedy01:31 Pharma model and 10 minute med checks02:37 Framing the crisis and why patients feel stuck05:49 How psychiatry arrived at symptom based meds07:29 What to test, hormones and core nutrients10:49 The Whole Body Map explained12:39 Vitamin D, B12, iron, thyroid, practical targets17:52 Why meds fail without nutrition18:23 Eating disorders, zinc, omega 3, methylfolate24:33 MTHFR, folate, and glutathione26:34 Nutrigenomics and personalized dosing29:51 Ketamine and psychedelics, proceed with caution32:26 Lithium orotate, irritability and dementia research38:57 Polypharmacy, slowing down, doing the work43:21 ADHD, diet, sleep, screens, lifestyle links46:28 Where to learn more, resources, closing (00:00) - Chapter 1 (00:00) - Introduction, testing gap and the B12 tragedy (01:31) - Pharma model and 10 minute med checks (02:37) - Framing the crisis and why patients feel stuck (05:49) - How psychiatry arrived at symptom based meds (07:29) - What to test, hormones and core nutrients (10:49) - The Whole Body Map explained (12:39) - Vitamin D, B12, iron, thyroid, practical targets (17:52) - Why meds fail without nutrition (18:23) - Eating disorders, zinc, omega 3, methylfolate (24:33) - MTHFR, folate, and glutathione (26:34) - Nutrigenomics and personalized dosing (29:51) - Ketamine and psychedelics, proceed with caution (32:26) - Lithium orotate, irritability and dementia research (38:57) - Polypharmacy, slowing down, doing the work (43:21) - ADHD, diet, sleep, screens, lifestyle links (46:28) - Where to learn more, resources, closing

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