1. Launch of TrumpRx.gov
The White House announced and launched TrumpRx.gov, a federal website designed to provide Americans access to significantly discounted prescription drugs.
The platform allows patients with valid prescriptions to obtain savings via manufacturer-supported coupons, downloadable or printable, integrated through the website.
2. Most Favored Nation (MFN) Drug Pricing Model
The initiative is based on Most Favored Nation pricing, meaning U.S. patients pay prices comparable to the lowest prices paid by other developed nations.
The document argues Americans have historically overpaid due to pharmaceutical lobbying and systemic corruption, which MFN pricing aims to correct.
3. Pharmaceutical Manufacturer Participation
Initial participating manufacturers include: AstraZeneca
Eli Lilly
Novo Nordisk
Pfizer
Additional drugs and manufacturers are expected to be added over time as more MFN pricing agreements are finalized.
4. Major Drug Price Reductions (Examples)
The document highlights dramatic price cuts on high‑cost, high‑usage medications:
Diabetes & Weight‑Loss Drugs Ozempic‑type injectables: ~$1,000+ → as low as $199/month
Wegovy: ~$1,349 → as low as $149
Zepbound: ~$1,088 → as low as $299–$346
Insulin Available for as low as $25/month
Respiratory Medications COPD inhalers: ~$500 → $51
Asthma inhalers: ~$504 → $201
Menopause/Osteoporosis Drug Duavee: ~$202 → $30
These examples are presented as evidence of the “largest prescription drug price reduction in U.S. history.”
5. Fertility Drug Cost Relief
Fertility medications are emphasized as a major priority due to high out‑of‑pocket costs.
Families may save over $2,000 per IVF cycle on average.
Example reductions include: One fertility drug reduced to $168 per pen
Another reduced to $22–$50
Personal testimony is used to highlight the financial burden of infertility treatments.
6. Policy and Legislative Timeline
Key policy milestones cited in the document:
May 12, 2025 – Executive Order signed: Delivering Most Favored Nation Prescription Drug Pricing to American Patients
July 31, 2025 – Letters sent to major drug manufacturers outlining required price reductions
Since September 2025 – 16 MFN pricing deals announced with pharmaceutical companies
December 1, 2025 – Agreement with the UK to raise its drug prices by 25%, shifting more costs overseas
January 15, 2026 – Call for Congress to pass the “Great Healthcare Plan” to codify savings and increase transparency
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