Infectious Disease Puscast

On episode #119 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 10/27 – 11/9/26.
Hosts: Daniel Griffin and Sara Dong
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Links for this episode
Viral
FDA Approves First Plasmid DNA-based Immunotherapy for Adults with Recurrent Respiratory Papillomatosis (FDA)
A DNA Shot Against Warts in the Throat: How Voceryq Works (YouTube)
Bacterial
Doxycycline versus azithromycin as combination therapy in the empirical treatment of community-acquired pneumonia in an intensive care unit – A retrospective propensity score-matched cohort study (Journal of Microbiology, Immunology and Infection)
Gram-Negative Bacterial Resistance (NEJM)
Performance of the recent Duke criteria versions in patients with suspected infective endocarditis and sufficient cardiac imaging: The more things change, the more they remain the same (CID)
Comparative effectiveness of trimethoprim-sulfamethoxazole dosing strategies for Pneumocystis jirovecii pneumonia: a target trial emulation (Clinical Microbiology and Infection)
Is a lower dose of trimethoprim sulfamethoxazole for Pneumocystis jirovecii pneumonia just as effective, but safer? (Clinical Microbiology and Infection)
State-of-the-Art Review: Native Joint Septic Arthritis Epidemiology, Pathogenesis, Microbiology, Diagnosis, Management, and Outcomes (CID)
Fungal
The Last of US Season 2 (YouTube)
Parasitic
Cryptosporidium parvum Outbreak Among Volunteers of a Licensed Wildlife Rehabilitation Center Housing Raccoons, 2024 (JID)
Proactive Surveillance of Public Swimming Pools to Prevent Delayed Detection of Cryptosporidiosis Outbreaks (JID)
Immunity and vaccines for cryptosporidiosis (JID)
Cryptosporidiosis at a Crossroads (JID)
Miscellaneous
Pediatric Fellowship Training in Immunocompromised and Transplant Infectious Diseases: Developing Expertise in Caring for Immunocompromised Children (Transplant Infectious Disease)
The magnitude and durability of immune response to the SARS-CoV-2 vaccination among children (Journal of the Pediatric Infectious Diseases Society)
Music is by Ronald Jenkees
Information on this podcast should not be considered as medical advice.

On episode #118 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 10/13 – 10/26/26.
Host: Daniel Griffin
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Links for this episode
Viral
Alimatravir Oral Once Monthly in Adults With Low Likelihood of HIV Exposure: A Randomized, Double-Blind, Placebo-Controlled Study (JID)
Long-Acting Lenacapavir and Cabotegravir and Viral Suppression Among People With HIV (JAMA: Open Network)
FDA Approves First-of-Its-Kind Chronic Hepatitis B Treatment (FDA)
Phase 3 Results of Bepirovirsen Treatment for Chronic Hepatitis B Virus Infection (NEJM)
Safety, tolerability and antiviral activity of the antisense oligonucleotide bepirovirsen in patients with chronic hepatitis B: a phase 2 randomized controlled trial (Nature Medicine)
Bacterial
A Systematic Review and Network Meta-analysis of Empirical Antibiotics for Complicated Urinary Tract Infections (OFID)
Cephalexin 500 mg Four Times Daily vs. 1000 mg Three Times Daily for the Treatment of Uncomplicated Cellulitis (OFID)
Fungal
The Last of US Season 2 (YouTube)
Performance of the Urinary MycoMEIA Aspergillus Assay as an Aid to Diagnose Invasive Aspergillosis (CID)
Emergence of pan-drug resistant Candidozyma auris in Kenya, the second globally documented case(Scientific Reports)
Parasitic
Artificial Intelligence–Supported Automated Microscopy for Malaria Diagnosis: A Multicenter Study (CID)
Decentralized Diagnostic Platform, miLab™ (noul)
Mapping Hospitals That Treat Severe Malaria Cases in the United States: Evidence to Inform Health Systems Strategies for Intravenous Artesunate Supply (CID)
Locally Acquired Malaria Cases Identified in the United States (CDC: Emergency Preparedness and Response)
ARTESUNATE FOR INJECTION (AMIVAS)
Availability of IV Artesunate for Severe Malaria (CID)
Miscellaneous
Response-Tailored or Standard-Duration Antibiotic Treatment for Infective Endocarditis (NEJM)
Music is by Ronald Jenkees
Information on this podcast should not be considered as medical advice.

On episode #117 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 9/29 – 10/12/26.
Hosts: Daniel Griffin and Sara Dong
Subscribe (free): Apple Podcasts, RSS, email
Become a patron of Puscast!
Links for this episode
Viral
Influenza Vaccine Effectiveness Against Influenza A–Associated Hospitalization and Severe In-Hospital Outcomes Among Adults in the United States, 2024–2025 (CID
Risk Factors for Hypoxia, Mechanical Ventilation, and Mortality in Lung Transplant Recipients Hospitalized with Respiratory Syncytial Virus: A Multicenter International Cohort Study (OFID)
Bacterial
R.E.M. – It's The End Of The World (YouTube)
Mandatory infectious diseases consultation and consensus approach effective at lowering antibiotic duration in uncomplicated gram-negative bacteremia (Journal of Gastroenterology and Hepatology)
Air contamination and cross-room transmission of carbapenem resistant Acinetobacter baumannii in ICU (Antimicrobial Stewardship & Healthcare Epidemiology)
Uncovering an alternate pathway of antibiotic resistance in spore-forming bacteria (Nature Communications)
Clinical Practice Guideline for the Diagnosis and Treatment of Urinary Tract Infection in Children From 8 Days to 5 Years of Age (Pediatrics)
Shorter Antibiotic Duration for Pseudomonas Bacteremia: A Call for Future Trials (CID)
Fungal
The Last of US Season 2 (YouTube)
Impact of a Large-Scale Mold Intervention in Public Housing on Asthma Emergency Department Visits (American Journal of Respiratory and Critical Care Medicine)
A Candid Appraisal of Repeat Blood Cultures in Candidemia—Missed Detection or Incident Infection? (CID)
Notes from the Field: Molecular Detections of Cladophialophora bantiana at a Clinical Reference Laboratory — United States, 2009–2026 (CDC: MMWR)
Histoplasmosis in Pregnancy: A Review and Patient Perspective (OFID)
Parasitic
Flubendazole reduces emerging Dracunculus medinensis in dogs in Chad: Results from a two-year study (PLoS Neglected Tropical Diseases)
Toxoplasma Transmission to the Fetus during the Periconceptional Period (AJTMH: American Journal of Tropical Medicine and Hygiene)
Clinical and Laboratory Dynamics of Bear Meat-Associated Trichinellosis in Hokkaido, Japan (AJTMH: American Journal of Tropical Medicine and Hygiene)
Clinical significance of Dientamoeba fragilis and Blastocystis: Lessons from clinical trials, cohort studies, and faecal microbiota transplantation — a narrative review (CMI: Clinical Microbiology and Infection)
Miscellaneous
A consensus-based guideline for personalized bacteriophage therapy (Nature Medicine)
Diagnosis and Management of Infectious Encephalitis in Adults: Guidelines From the European Academy of Neurology and European Society of Clinical Microbiology and Infectious Diseases (European Journal of Neurology)
Music is by Ronald Jenkees
Information on this podcast should not be considered as medical advice.

On episode #116 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 9/16 – 9/21/26.
Hosts: Daniel Griffin and Sara Dong
Subscribe (free): Apple Podcasts, RSS, email
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Links for this episode
Viral
Oya Virus in a Patient with Severe Hepatitis, Enteritis, and Coagulopathy (NEJM)
Two Versus One COVID-19 Vaccine Dose After Prior SARS-CoV-2 Infection: A Nationwide Retrospective Cohort Study (OFID)
Comparison of Silevimig, a Novel Bispecific Anti-Rabies Monoclonal Antibody, with Human Rabies Immunoglobulin for Post-Exposure Prophylaxis: A Phase III, Randomized, Double-Blind, Non-Inferiority Trial (CID)
Bacterial
R.E.M. – It's The End Of The World (YouTube)
Companion Animals Harbour Globally Circulating Human-Associated Klebsiella pneumoniae Lineages and High-Risk Antimicrobial Resistance Clones (Transboundary and Emerging Diseases)
Air contamination and cross-room transmission of carbapenem resistant Acinetobacter baumannii in ICU (American Journal of Infection Control)
Economic Outcomes of Dalbavancin versus Standard Therapy in Staphylococcus aureus Bacteremia in the DOTS Randomized Clinical Trial (CID)
Cephalexin Model-Informed Dosing Recommendations for Severe Infections: A Pooled Pharmacokinetic Analysis From Infancy to Adulthood (OFID)
Initial Carbapenem Choice Versus Sustained Single-Group Therapy in the Albumin-Carbapenem Interaction (CID)
Identification and Quantification of Pathogens in Pleural Fluid from Children with Complicated Pneumonia using the BioFire® FilmArray® Pneumonia Panel (Journal of Pediatric Infectious Diseases Society)
Effectiveness of oral care for the prevention of non-ventilator hospital-acquired pneumonia (HAPPEN): a multicentre, stepped-wedge, cluster-randomised trial in Australia (LANCET: Infectious Diseases)
Fungal
The Last of US Season 2 (YouTube)
Health Economic Analysis of the AMBITION Protocol for Human Immunodeficiency Virus–Associated Cryptococcal Meningitis in the United States (CID)
Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis (NEJM)
Parasitic
Vampire bats in Belize harbor multiple Trypanosoma cruzi genotypes: Implications for parasite transmission at the wildlife–domestic–human interface (PLoS Neglected Tropical Diseases)
Community-acquired coinfections in adults with severe imported malaria: a systematic review and meta-analysis (CMI: Clincial Microbiology and Infection)
Treatment for Leishmaniasis using liposomal amphotericin for immune compromised patients (in Portguese(Brazil.gov))
Reactivation of Cutaneous Leishmaniasis in a Rheumatoid Arthritis Patient Undergoing Tocilizumab Treatment (AJTMH: American Journal of Tropical Medicine and Hygiene)
Efficacy and safety of alternative benznidazole and nifurtimox regimens for adults with chronic Trypanosoma cruzi infection (TESEO): an open-label, randomised, non-inferiority phase 2b trial (LANCET: Infectious Diseases)
Music is by Ronald Jenkees
Information on this podcast should not be considered as medical advice.

On episode #115 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 9/1 – 9/14/26.
Hosts: Daniel Griffin and Sara Dong
Subscribe (free): Apple Podcasts, RSS, email
Become a patron of Puscast!
Links for this episode
Viral
Immunogenicity of fractional one-fifth and one-half doses of 17DD yellow fever vaccine compared with full dose in children aged 9–23 months in Uganda: a phase 4, single-blind, randomised clinical trial (The LANCET)
Early Antiviral Therapy in Pediatric Outpatients and Risk of Influenza-Related Hospitalization (Pediatrics)
Beyond Koplik spots: aphthous-like ulcers as a novel enanthem in adolescent and adult measles (CMI: Clinical Microbiology and Infection)
Bacterial
A Ten-Year Trend of Antimicrobial Resistance in Pseudomonas aeruginosa From United States Medical Centers: Results From the INFORM Surveillance Program (2015–2024)(OFID)
A Scenario-Based Survey of Clinician Recommendations for Follow-up Blood Cultures in Patients with Varying Risk of Persistent Gram-Negative Bacteremia (OFID)
Should valve leaflet thickening be considered a characteristic lesion of infective endocarditis? (CID)
Infective Endocarditis: Diagnosis, Antibiotic Therapy, and Management: A Scientific Statement From the American Heart Association (AHA|ASA: Circulation)
IDSA/ESCMID 2026 Consensus Statements on Staphylococcus aureus Bacteremia: Risk Stratification, Diagnostic Evaluation, and Management of Adults and Children (IDSA)
Relationship between Antibiotic Prescription and Survival in Hospice (CID)
Performance and Projected Impact of Synovial Fluid Polymerase Chain Reaction Testing for Patients Evaluated for Septic Arthritis (CID)
Cefepime versus piperacillin-tazobactam for the treatment of Pseudomonas aeruginosa pneumonia (CID)
Cefepime and Mortality A Systematic Review and Bayesian Meta-Analysis (JAMA: OPEN Network)
Global and regional burden of colorectal cancer potentially related to Helicobacter pylori exposure: a risk attribution modelling study (BMJ Journals: eGastroenterology)
A randomized controlled trial of cefiderocol versus standard therapy for Gram-negative bacterial bloodstream infections: Benefit and risk assessment using DOOR and generalized pairwise comparisons (CID)
Fungal
The Last of US Season 2 (YouTube)
No survival benefit associated with antifungal therapy for respiratory Candida spp.: a single-center retrospective cohort study (OFID)
The Role of 1-3-Beta-D-Glucan in Predicting Pneumocystis jirovecii Pneumonia in Immunocompromised Children (Journal of the Pediatric Infectious Diseases Society)
Parasitic
Miscellaneous
Vaccination Coverage Among Adolescents Aged 13–17 Years — National Immunization Survey-Teen, United States, 2025 (CDC:MMWR)
Music is by Ronald Jenkees
Information on this podcast should not be considered as medical advice.