Infectious Disease Puscast

On episode #116 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 9/16 – 9/21/26.
Hosts: Daniel Griffin and Sara Dong
Subscribe (free): Apple Podcasts, RSS, email
Become a patron of Puscast!
Links for this episode
Viral
Oya Virus in a Patient with Severe Hepatitis, Enteritis, and Coagulopathy (NEJM)
Two Versus One COVID-19 Vaccine Dose After Prior SARS-CoV-2 Infection: A Nationwide Retrospective Cohort Study (OFID)
Comparison of Silevimig, a Novel Bispecific Anti-Rabies Monoclonal Antibody, with Human Rabies Immunoglobulin for Post-Exposure Prophylaxis: A Phase III, Randomized, Double-Blind, Non-Inferiority Trial (CID)
Bacterial
R.E.M. – It's The End Of The World (YouTube)
Companion Animals Harbour Globally Circulating Human-Associated Klebsiella pneumoniae Lineages and High-Risk Antimicrobial Resistance Clones (Transboundary and Emerging Diseases)
Air contamination and cross-room transmission of carbapenem resistant Acinetobacter baumannii in ICU (American Journal of Infection Control)
Economic Outcomes of Dalbavancin versus Standard Therapy in Staphylococcus aureus Bacteremia in the DOTS Randomized Clinical Trial (CID)
Cephalexin Model-Informed Dosing Recommendations for Severe Infections: A Pooled Pharmacokinetic Analysis From Infancy to Adulthood (OFID)
Initial Carbapenem Choice Versus Sustained Single-Group Therapy in the Albumin-Carbapenem Interaction (CID)
Identification and Quantification of Pathogens in Pleural Fluid from Children with Complicated Pneumonia using the BioFire® FilmArray® Pneumonia Panel (Journal of Pediatric Infectious Diseases Society)
Effectiveness of oral care for the prevention of non-ventilator hospital-acquired pneumonia (HAPPEN): a multicentre, stepped-wedge, cluster-randomised trial in Australia (LANCET: Infectious Diseases)
Fungal
The Last of US Season 2 (YouTube)
Health Economic Analysis of the AMBITION Protocol for Human Immunodeficiency Virus–Associated Cryptococcal Meningitis in the United States (CID)
Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis (NEJM)
Parasitic
Vampire bats in Belize harbor multiple Trypanosoma cruzi genotypes: Implications for parasite transmission at the wildlife–domestic–human interface (PLoS Neglected Tropical Diseases)
Community-acquired coinfections in adults with severe imported malaria: a systematic review and meta-analysis (CMI: Clincial Microbiology and Infection)
Treatment for Leishmaniasis using liposomal amphotericin for immune compromised patients (in Portguese(Brazil.gov))
Reactivation of Cutaneous Leishmaniasis in a Rheumatoid Arthritis Patient Undergoing Tocilizumab Treatment (AJTMH: American Journal of Tropical Medicine and Hygiene)
Efficacy and safety of alternative benznidazole and nifurtimox regimens for adults with chronic Trypanosoma cruzi infection (TESEO): an open-label, randomised, non-inferiority phase 2b trial (LANCET: Infectious Diseases)
Music is by Ronald Jenkees
Information on this podcast should not be considered as medical advice.

On episode #115 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 9/1 – 9/14/26.
Hosts: Daniel Griffin and Sara Dong
Subscribe (free): Apple Podcasts, RSS, email
Become a patron of Puscast!
Links for this episode
Viral
Immunogenicity of fractional one-fifth and one-half doses of 17DD yellow fever vaccine compared with full dose in children aged 9–23 months in Uganda: a phase 4, single-blind, randomised clinical trial (The LANCET)
Early Antiviral Therapy in Pediatric Outpatients and Risk of Influenza-Related Hospitalization (Pediatrics)
Beyond Koplik spots: aphthous-like ulcers as a novel enanthem in adolescent and adult measles (CMI: Clinical Microbiology and Infection)
Bacterial
A Ten-Year Trend of Antimicrobial Resistance in Pseudomonas aeruginosa From United States Medical Centers: Results From the INFORM Surveillance Program (2015–2024)(OFID)
A Scenario-Based Survey of Clinician Recommendations for Follow-up Blood Cultures in Patients with Varying Risk of Persistent Gram-Negative Bacteremia (OFID)
Should valve leaflet thickening be considered a characteristic lesion of infective endocarditis? (CID)
Infective Endocarditis: Diagnosis, Antibiotic Therapy, and Management: A Scientific Statement From the American Heart Association (AHA|ASA: Circulation)
IDSA/ESCMID 2026 Consensus Statements on Staphylococcus aureus Bacteremia: Risk Stratification, Diagnostic Evaluation, and Management of Adults and Children (IDSA)
Relationship between Antibiotic Prescription and Survival in Hospice (CID)
Performance and Projected Impact of Synovial Fluid Polymerase Chain Reaction Testing for Patients Evaluated for Septic Arthritis (CID)
Cefepime versus piperacillin-tazobactam for the treatment of Pseudomonas aeruginosa pneumonia (CID)
Cefepime and Mortality A Systematic Review and Bayesian Meta-Analysis (JAMA: OPEN Network)
Global and regional burden of colorectal cancer potentially related to Helicobacter pylori exposure: a risk attribution modelling study (BMJ Journals: eGastroenterology)
A randomized controlled trial of cefiderocol versus standard therapy for Gram-negative bacterial bloodstream infections: Benefit and risk assessment using DOOR and generalized pairwise comparisons (CID)
Fungal
The Last of US Season 2 (YouTube)
No survival benefit associated with antifungal therapy for respiratory Candida spp.: a single-center retrospective cohort study (OFID)
The Role of 1-3-Beta-D-Glucan in Predicting Pneumocystis jirovecii Pneumonia in Immunocompromised Children (Journal of the Pediatric Infectious Diseases Society)
Parasitic
Miscellaneous
Vaccination Coverage Among Adolescents Aged 13–17 Years — National Immunization Survey-Teen, United States, 2025 (CDC:MMWR)
Music is by Ronald Jenkees
Information on this podcast should not be considered as medical advice.

On episode #114 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 8/18 – 8/31/26.
Hosts: Daniel Griffin and Sara Dong
Subscribe (free): Apple Podcasts, RSS, email
Become a patron of Puscast!
Links for this episode
Viral
HPV Vaccination and Risk of Head and Neck Cancers: A Large Real-World Cohort Study (International Society for Infectious Diseases)
Beyond the Acute Illness: Three Myths About Viral RespiratoryInfection (JID)
Use of Nowcasting to Estimate Real-Time Transmission Trends During a Measles Outbreak — South Carolina, October 2025–March 202 (CDC: MMWR)
IPOL (Package Insert)
Effect of inactivated poliovirus vaccine on nasal mucosal immunity and pharyngeal shedding following novel oral poliovirus vaccine type 2 challenge: A randomized, open-label trial (JID)
Bacterial
Response-Tailored or Standard-Duration Antibiotic Treatment for Infective Endocarditis (NEJM)
Clinical Practice Guidelines by Infectious Diseases Society of America 2025 Guidelines on Management and Treatment of Complicated Urinary Tract Infections–Introduction and Methods (CID)
Society of America: 2025 Guideline on Management and Treatment of Complicated Urinary Tract Infections–Selection of Antibiotic Therapy for Complicated Urinary Tract Infections (CID)
Clinical Practice Guidelines by Infectious Diseases Society of America: 2025 Guidelines on Management and Treatment of Complicated Urinary Tract Infections – Timing of Intravenous to Oral Antibiotics Transition for Complicated Urinary Tract Infections (CID)
Clinical Practice Guidelines by Infectious Diseases Society of America (IDSA): 2025 Guidelines on Management and Treatment of Complicated Urinary Tract Infections–Duration of Antibiotics for Complicated UTI (CID)
Infective Endocarditis in Solid Organ and Haematopoietic Stem Cell Transplant Recipients (E-IPA Study): a propensity-score-matched retrospective cohort study (CID)
Evaluation of Changes in Staphylococcus and Enterococcus Resistance Following Reduced Restrictions on Daptomycin and Linezoli (OFID)
Comparison of VPM1002 with BCG in the prevention of tuberculosis in newborn infants: a multicentre, double-blind, randomised, phase 3, non-inferiority trial (LANCET: Infectious Diseases)
Fungal
The Last of US Season 2 (YouTube)
Containment of a Candidozyma auris Outbreak in an Acute Care Hospital using a Comprehensive Screening and Surveillance Program (CID)
Molecular Evidence of Autochthonous Environmental Acquisition of Fonsecaea Pediatric Infection in the United States (OFID)
Challenging the concept of uncomplicated candidemia for shorter courses of antifungal therapy (OFID)
Parasitic
Miscellaneous
Reliability of Physical Examination Findings in Youths Diagnosed With Pneumonia (JAMA)
Recombinant shingles vaccination and the risk of cardiovascular events (Nature Medicine)
Music is by Ronald Jenkees
Information on this podcast should not be considered as medical advice.

On episode #113 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 8/4 – 8/17/26.
Hosts: Daniel Griffin and Sara Dong
Subscribe (free): Apple Podcasts, RSS, email
Become a patron of Puscast!
Links for this episode
Viral
Two-year durability of MVA-BN vaccine-induced antibodies and the risk of Mpox breakthrough infections among high-risk populations: a prospective, longitudinal study (CMI: Clinial Microbiology and Infection)
Notes from the Field: Potential Infant HIV Exposure from Donated Breast Milk Received Through Social Media — Santa Clara County, California, May 2025–January 2026 (CDC: MMWR)
Bacterial
Associations Between QuantiFERON-TB Gold Plus IFNγ Concentrations and Progression to Symptomatic Tuberculosis in Global High-Burden TB Settings (OFID)
Cefadroxil as Oral Transitional Therapy for Gram-Positive Bacteremia With or Without Non-Vertebral Osteomyelitis: A Multicenter Retrospective Cohort Study (OFID)
Efficacy of beta-lactam monotherapy versus clindamycin or addition of metronidazole in peritonsillar abscess – an observational cohort study with a focus on Fusobacterium necrophorum (CMI: Clinial Microbiology and Infection)
A novel RNA nucleic acid amplification test more accurately distinguishes active Clostridioides difficile infection from colonization (CID)
The Clean Margin in Diabetic Foot Osteomyelitis: Conceptual Appeal, Practical Uncertainty (CID)
Rising Incidence of New Delhi Metallo-β-Lactamase–Producing Carbapenem-Resistant Enterobacterales, 10 US Sites, 2018–2023 (OFID)
Association of anti-anaerobic antibiotics with mortality and the gut microbiome: a sub-study of the BALANCE randomized clinical trial (CID)
Fungal
The Last of US Season 2 (YouTube)
Coccidioidomycosis Testing Among Patients Hospitalized With Community-Acquired Pneumonia (OFID)
Parasitic
Human Myiasis Resulting from Reemergence of Cochliomyia hominivorax Screwworm, Mexico, 2025–2026 (Emerging Infectious Diseases)
The origin, history, and resistance architecture of an invasive urban malaria mosquito in Africa (Science)
Clinical, molecular, and in vitro evidence of artemisinin partial resistance in Ethiopian Plasmodium falciparum: a prospective, multisite, surveillance (LANCET: Infectious Diseases)
Miscellaneous
What's in a Name? Etymology and History of Antibacterials and Antifungal (IOFID)
Music is by Ronald Jenkees
Information on this podcast should not be considered as medical advice.

On episode #112 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 7/20 – 8/3/26.
Host: Daniel Griffin and Sara Dong
Subscribe (free): Apple Podcasts, RSS, email
Become a patron of Puscast!
Links for this episode
Viral
The genomic identity of early smallpox in South America (Science)
Telltale DNA: First direct evidence found that the Spanishbrought smallpox to the Inca (CIDRAP)
Phase 3 Trial of Weekly Oral Islatravir–Lenacapavir for HIV-1 Treatment (NEJM)
Early Transcriptional Signature in Chikungunya PredictsChronic Arthralgia and Reveals Deficient Antiviral Response (JID)
Bacterial
IDSA 2026 Guidance on the Treatment of Antimicrobial Resistant Gram-Negative Infections (IDSA)
Doxycycline in the treatment of outpatient mild community-acquired pneumonia: a propensity-matched retrospective cohort study (CMI: Clinical Microbiology and Infection)
Detection of pathogens in the gut microbiome priorto bloodstream infection in children with acute myeloid leukemia or mature B-cell non-Hodgkin lymphoma (Journal of Pediatric Infectious Diseases Society)
Fungal
The Last of US Season 2 (YouTube)
Active Surveillance for Invasive Mold Disease — Four Hospitals, Atlanta, Georgia, 2020–2024 (CDC: MMWR)
Does the Evidence Support High-Dose Liposomal Amphotericin B in the Treatment of Mucormycosis? (JID)
Miscellaneous
Evaluation of the impact of a novel surgical handwashing method on reformation of microbial flora on surgeons' hands (Infection Control & Hospital Epidemiology)
Association Between First MMR Vaccination Before Age 2 Years and Childhood Autism in a U.S. EHR Cohort of 2.5 Million Children (Journal of Pediatric Infectious Diseases Society)
Music is by Ronald Jenkees
Information on this podcast should not be considered as medical advice.