UnHack with Drex DeFord

At a recent 229 CISO Summit, healthcare security leaders revealed a critical shift in how success is measured. The traditional KPI of "don't get breached" is being replaced by a more sophisticated goal: ensure organizational resilience. Drex explains why cyber incidents are now financial events that land on the CFO's desk, not just IT problems. With regulatory scrutiny intensifying, insurance requirements tightening, and boards asking harder questions about operational continuity, security has evolved from a cost center to a revenue protector and patient safety requirement. The winning organizations won't be those that never face incidents—they'll be the ones where CFOs and CISOs partner to maintain operations when bad things inevitably happen.
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February 9, 2026: Bill Russell, Drex DeFord, and Sarah Richardson dissect J.P. Morgan healthcare presentations to reveal what's really being asked of technology leaders in 2026. The era of transformation talk is over; executives want friction reduced, margins improved, and growth enabled. Bill shares insights from CMIO conversations showing leaders moving beyond EHR optimization to solve real business challenges around patient access and clinical workflows. Drex and Sarah debate whether the shift toward operational excellence means CIOs should prepare to run pharmacy and lab departments next.
Key Points:
04:26 Challenges and Opportunities in Healthcare IT
10:17 Cybersecurity and Operational Focus
17:17 EHR Systems and Operational Efficiency
23:11 Hostage Crisis and Final Thoughts
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Drex explores a fundamental shift in AI: agents that don't wait for prompts, persist indefinitely, and now learn from each other through social platforms. Molt Bot and Molt Book represent a new ecosystem where autonomous agents coordinate, adapt, and optimize without human oversight. This isn't about sentient AI—it's about delegation without governance. For healthcare leaders, the urgent question isn't whether this matters, but whether you know which agents are already operating in your environment. The shift from "human in the loop" to "human on the loop" is already happening.
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February 2, 2026: Are health systems being sidelined from healthcare's innovation revolution? Jason Rose, CEO of Clearsense, joins This Week Health fresh from the J.P. Morgan Conference to challenge the narrative that providers are absent from innovation discussions. Jason reveals what really happened inside JPM's exclusive health system presentations, from CEOs prioritizing AI transformation to CFOs rising as the new power players driving technology strategy. The conversation explores why app rationalization remains the unglamorous financial lever that unlocks innovation budgets, and why simplification might be healthcare's most underrated competitive advantage in 2026.
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Key Points:
02:20 JPM Conference Insights
07:07 CEO and CFO Perspectives
13:54 Application Rationalization Challenges
22:40 Conclusion and Final Thoughts

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On Data Privacy Day, Drexon challenges healthcare leaders to move beyond compliance checkboxes and recognize privacy as a core component of "do no harm." As patient data flows through EHRs, cloud platforms, and AI systems, the responsibility to protect that trust doesn't live in policies—it lives with leadership. When data is over-collected or loosely governed, patients start holding back, and the critical trust between medical teams and patients begins to fracture. This year, data privacy should be about ownership: who decides what data we truly need, and who's willing to say no even when technology makes it easy?
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