Rapamycin is changing what's possible in fertility treatment, and in this episode, I'm breaking down exactly how. Originally discovered in the soil of Easter Island and long used by the longevity community to extend healthspan, rapamycin is now showing real promise for improving egg quality, increasing blastocyst formation rates, and helping women over 40 (even over 45) get pregnant.
Joining me is Dr. Steve Palter, founder and medical and scientific director of Gold Coast IVF in Woodbury, New York.
We cover the science of how it works at the cellular level, the landmark placebo-controlled trial out of China that gave us published data for the first time, my own case series accepted to PCRS, and how I'm now using Rapamycin for egg freezing patients, not just last-resort IVF cases. We also get discuss the Vibrant Trial on ovarian aging, dosing protocols, and why resistance training and protein intake matter for fertility and longevity.
In this episode, we cover:
• What rapamycin is, where it comes from, and why it's become the darling of the longevity world
• How rapamycin may improve egg quality by regulating protein synthesis and cellular repair in aging ovarian cells
• The landmark placebo-controlled trial out of China showing significantly higher pregnancy rates in poor-prognosis patients
• My own case series (including patients over 45 getting pregnant) accepted to PCRS
• Who is (and isn't) a good candidate, and how to have that conversation with your doctor
• Why dosing protocols are still evolving and what current regimens look like
• The underrated role of resistance training and protein intake for fertility, PCOS, and longevity
Read the full show notes, and find the full length episode here.
Resources:
Dr. Steve Palter on Instagram, TikTok & Facebook: @StevenPalterMD
Gold Coast IVF: goldcoastivf.com
Dr. Palter's PCOS metabolic reset program: pcosbaby.com
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The next live class call is on Monday, July 13, 2026 at 4pm PST, where Dr. Aimee will explain IVF and there will be time to ask her your questions live on Zoom.
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Dr. Aimee Eyvazzadeh is one of America's most well known fertility doctors. Her success rate at baby-making is what gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org.