The Egg Whisperer Show

Read the full episode notes:  https://www.draimee.org/imputepgta-and-pgt-p-explained-the-latest-in-polygenic-embryo-testing-with-guest-jonathan-anomaly-of-herasight
 
Today I'm thrilled to dive into the world of polygenic embryo testing (PGTP) and ImputePGTA with my guest, Jonathan Anomaly, Director of Communications at Herasight.
 
In our conversation, we unpack the science and ethics behind polygenic testing, discuss how it differs from traditional embryo screening, and address the hopes and concerns that come with these new technologies. We talk about the real-world impact for patients, the importance of informed consent, and how families can make empowered choices about their reproductive journeys. Whether you're a patient, a provider, or just curious about the future of fertility medicine, this episode is packed with insights.
 
Get your copy of my new book, The Egg Whisperer Way, now available on my website.
 
In this episode, we cover:
 
The basics of PGTP and how it compares to PGTA and PGTM
Announcement of ImputePGTA,  a new technique that enables accurate polygenic embryo screening from a routine test (PGT-A)
How polygenic risk scores are developed and validated
The potential and limitations of predicting disease risk and traits in embryos
Ethical considerations and common misconceptions about "designer babies"
The role of family history and ancestry in genetic testing
How Herasight's technology can help patients with different backgrounds and needs
What the future holds for embryo testing, including IVG and gene editing
 
Resources:
 
Herasight: herasight.com
Jonathan Anomaly's website: jonathan-anomaly.com
Dr. Aimee's resources: draimee.org
IVF calculator and white papers (available on herasight.com)
Subscribe to the Egg Whisperer Show on YouTube and Spotify
 
Dr. Aimee Eyvazzadeh is one of America's most well known fertility doctors. Her success rate at baby-making is what gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org.

In this episode of The Egg Whisperer Show, I'm joined by Ashley Rocha, founder of Ladywell, to discuss natural approaches to balancing hormones and supporting fertility. Ashley is passionate about holistic health and provides guidance on how nutrition, lifestyle, and herbal medicine can play a key role in reproductive wellness.


In This Episode, We Cover:

How hormonal imbalances affect fertility and overall health
The role of nutrition and lifestyle in supporting reproductive wellness
How herbal medicine and holistic approaches can enhance fertility
Ways to reduce stress and manage environmental factors that disrupt hormones
The importance of personalized care when addressing hormone health
Read the full show notes on Dr. Aimee's website.

Visit Ladywell's Website

 
Get your copy of my new book, The Egg Whisperer Way, now available on my website.
 
Other ways to reach me:
Visit my YouTube channel for more fertility tips!


Subscribe to the newsletter to get updates.


Join Egg Whisperer School.


Request a Consultation with me.


Dr. Aimee Eyvazzadeh is one of America's most well-known fertility doctors. Her success rate at baby-making gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org.

I'm thrilled to welcome Dr. Meredith Provost to The Egg Whisperer Show for an essential conversation about weight, exercise, and fertility. Dr. Provost brings an incredible background to this discussion: she's a reproductive endocrinologist at Indiana Fertility Institute with degrees from NC State, McMaster University, and a PhD from Cambridge in the history and philosophy of science. As a former Division I volleyball player and athlete herself, she uniquely understands both the science and the practical realities of maintaining health while trying to conceive. Her approach is refreshingly balanced and evidence-based, making her the perfect expert to tackle these often-confusing topics.

Read the full show notes on Dr. Aimee's website
In this episode, we dive deep into how weight impacts fertility for both women and men, exploring the hormonal mechanisms behind these connections. Dr. Provost shares her compassionate, non-restrictive approach to helping patients optimize their health without extreme measures or body shaming. We discuss realistic dietary recommendations, the role of BMI in fertility outcomes, and what exercise is safe during different stages of fertility treatment, from IUI cycles to egg freezing, IVF, and early pregnancy. Her philosophy of "fertility is a marathon, not a race" resonates throughout our conversation, offering hope and practical guidance for anyone on their fertility journey.
In this episode, we cover:
How weight affects the communication between your brain and ovaries, impacting ovulation
The difference between how higher and lower BMI affects fertility in women versus men
Why eating "real food" matters more than following restrictive fad diets
Exercise guidelines during IUI, IVF, egg freezing, embryo transfer, and early pregnancy
The truth about BMI goals and why Dr. Provost doesn't restrict treatment based on weight alone
How to create sustainable lifestyle changes with accountability partners
Why you shouldn't eliminate all the healthy coping mechanisms (like exercise) when trying to conceive
Resources:
Indiana Fertility Institute: fertilityindy.com
Dr. Meredith Provost on Instagram: @meredithprovostmd
"The Obesity Code" by Dr. Jason Fung (mentioned for intermittent fasting information)
Online BMI calculators for tracking body mass index
Get your copy of my new book, The Egg Whisperer Way, now available on my website.
Other ways to follow Dr. Aimee:
Visit my YouTube channel for more fertility tips
Subscribe to the newsletter to get updates
Join The Egg Whisperer School
Request a Consultation with Dr. Aimee
 
Dr. Aimee Eyvazzadeh is one of America's most well‑known fertility doctors. Her success rate at baby‑making gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org.

Keywords: fertility and weight, BMI and fertility, exercise during IVF, diet for fertility, PCOS weight loss, fertility doctor Indianapolis, egg freezing exercise restrictions, embryo transfer activity, reproductive endocrinology, fertility nutrition, weight loss for conception, ovulation and BMI, male fertility and weight, intermittent fasting PCOS, IVF success rates, fertility marathon, Dr. Meredith Provost, Indiana Fertility Institute, The Egg Whisperer Show, Dr. Aimee Eyvazzadeh

I'm thrilled to introduce you to a groundbreaking innovation in fertility care: needle-free IVF. My guest is Dr. Rachel Mandelbaum, a fertility doctor, researcher, and patient advocate who is leading the charge to make IVF more accessible and less intimidating for everyone, especially those who are needle-phobic. Dr. Mandelbaum shares her personal journey, the inspiration behind her work, and how her innovations are changing the landscape of fertility treatment.
 
In our conversation, we dive deep into the themes of patient empowerment, challenging outdated norms in reproductive medicine, and the importance of offering more compassionate, personalized care. We discuss the science behind needle-free IVF, the impact of patient-centered innovation, and how small changes can make a big difference in the IVF experience. This episode is all about rethinking what's possible in fertility care and advocating for what patients truly deserve.
 
In this episode, we cover:
 
The inspiration behind needle-free IVF and Dr. Mandelbaum's personal journey as a patient and physician
How needle-free IVF works and the technology adapted from diabetes care
The results of clinical trials comparing needle-free IVF to traditional methods
Addressing patient fears and anxieties around self-injection and how new options can improve access to care
The importance of challenging the "just tough it out" mentality in women's health
Innovations in progesterone administration and reducing the need for painful injections
The future of IVF: personalized approaches, patient advocacy, and ongoing research
 
Resources:
 
Dr. Rachel Mandelbaum on Instagram: @rachel.mandelbaum.md
HRC Fertility: https://www.havingbabies.com/
The Egg Whisperer Show on YouTube: https://www.youtube.com/@eggwhisperershow
Subscribe to The Egg Whisperer Show on Spotify
Get The "Egg Whisperer Fertility Pants"
 
If you enjoyed this episode, be sure to subscribe and follow along for more conversations about fertility science, patient support, and taking charge of your reproductive health!
 
Get your copy of my new book, The Egg Whisperer Way, now available on my website.
 
Subscribe to my YouTube channel for more fertility tips!
Subscribe to the newsletter to get updates
 
Dr. Aimee Eyvazzadeh is one of America's most well known fertility doctors. Her success rate at baby-making is what gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org.

Can the surgeon you choose for your endometriosis surgery make or break your chances of getting pregnant? In this episode, I'm exploring what happens when endometriosis gets complicated: how to find the right surgeon, why imaging and surgical planning matter, and what it takes to protect your fertility when operating on reproductive organs.
My guest is Dr. Antonio Gargiulo, a reproductive endocrinologist and advanced reproductive surgeon in the Boston area. He has spent nearly three decades at the intersection of fertility and complex gynecologic surgery, with particular expertise in deep endometriosis, fibroids, adenomyosis, and fertility-focused minimally invasive and robotic surgery.
Read the full show notes on Dr. Aimee's website.

In this episode, we cover:

What makes endometriosis surgery complex and why deep endometriosis can involve other organs
How imaging and surgical planning can help identify the extent of disease before surgery
What questions to ask when choosing an endometriosis surgeon
How your surgeon's experience and approach can affect fertility outcomes
What we know about surgery for Stage I and II endometriosis and fertility
How to protect your fertility when endometriosis surgery involves reproductive organs
Why endometriosis requires long-term management, even after surgery

Resources:

Dr. Antonio Gargiulo's website: New England Endometriosis
Dr. Antonio Gargiulo on Instagram @AntonioGargiuloMd
The Italian Endometriosis Study (1990s)
The Canadian Endometriosis Study (late 1990s)
Opoien et al. (2017) — study on Stage I/II endometriosis ablation and IVF live birth rates
2019 Cochrane Database Review — GnRH agonist use before embryo transfer in IVF
AAGL and ASRM recommendations on progestin treatment for endometriosis management
Get your copy of my new book, The Egg Whisperer Way, now available on my website.
Dr. Aimee Eyvazzadeh is one of America's most well known fertility doctors. Her success rate at baby-making is what gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org.