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49ers Talk: A San Francisco 49ers Podcast

Matt Maiocco, NBC Sports Bay Area
49ers Talk: A San Francisco 49ers Podcast
Latest episode

948 episodes

  • 49ers Talk: A San Francisco 49ers Podcast

    49ers welcome reinforcements as CJ West joins growing injured list

    09/24/2026 | 41 mins.
    Second-year defensive tackle CJ West is the 49ers' latest IR casualty, joining a growing list of San Francisco players on the mend just three weeks into the season. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss how the 49ers can manage the early hits to their defensive line and wide receiver corps. Will the addition of Northern California native and NFL vet Brandin Cooks bridge the gap at wideout, or can Jordan Watkins finally break through? Later, Matt and Jennifer discuss Brock Purdy's phenomenal start -- and why coach Kyle Shanahan and running back Christian McCaffrey aren't surprised.

    --

    (0:00) 49ers bit by injury bug yet again
    (2:00) Why 49ers have interesting 53-man roster decisions to make
    (8:00) Brandin Cooks, other reinforcements arrive
    (14:00) Fifth WR spot shaping up to be week's biggest storyline
    (16:00) Why Brock Purdy's hot start isn't surprising
    (30:00) 49ers' rush defense gets more criticism than story stats tell
    (34:00) How will 49ers adjust defense with interior injuries?

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  • 49ers Talk: A San Francisco 49ers Podcast

    49ers dismantle Dolphins with offensive masterclass in Levi's home opener

    09/21/2026 | 35 mins.
    Brock Purdy and the 49ers were nearly perfect offensively in their 35-13 win over the Dolphins on Sunday at Levi's Stadium. San Francisco already has put the NFL on notice with their high-octane offense, and while its defense labored early in Week 2, the unit limited the Dolphins' production. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss just how far Brock Purdy has come since his 2022 debut against Miami, the impact of even more wide-receiver injuries, and which 49ers defender could bolster their interior line in the coming weeks if his practice window opens.
    --
    (0:00) George Kittle leads off the show
    (3:00) 49ers' bend-don't-break defense put emphasis on bend
    (10:00) WR room suffers another injury
    (18:00) Mike Evans, Kyle Juszczyk discuss reading route trees and QB options
    (19:00) Purdy's processing ability remains elite; Joe Montana, Steve Young vouch for it
    (28:00) Looking ahead to Week 3 vs. Cardinals

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  • 49ers Talk: A San Francisco 49ers Podcast

    Kyle Shanahan details key matchups in 49ers’ Week 2 game vs. Dolphins

    09/19/2026 | 37 mins.
    “49ers Talk” co-hosts Matt Maiocco and Jennifer Lee Chan preview San Francisco’s Week 2 game against the Miami Dolphins on Sunday at Levi’s Stadium. Then, they discuss the challenges San Francisco faces while recovering from their trip to Melbourne, Australia last week. Finally, Matt sits down with coach Kyle Shanahan to break down some key matchups in their upcoming game against a young, explosive Dolphins squad.
    --
    (1:39) Matt, Jennifer preview 49ers’ home opener vs. Miami on Sunday
    (2:54) Latest injury updates entering Week 2 matchup
    (7:45) Assessing 49ers' receiver depth after De'Zhaun Stribling injury
    (10:57) Will Kaelon Black suit up against the Dolphins?
    (19:21) Kyle Shanahan discuss challenges recovering from trip to Australia
    (20:59) Kyle breaks down 49ers’ weekly schedule during the regular season
    (33:12) How linebacker Fred Warner still amazes Kyle every day
    (35:07) Challenges of facing young Dolphins team

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  • 49ers Talk: A San Francisco 49ers Podcast

    How De'Zhaun Stribling, Jake Tonges injuries will test 49ers' offensive depth

    09/17/2026 | 36 mins.
    It came as no surprise when 49ers coach Kyle Shanahan announced Wednesday that wide receiver De'Zhaun Stribling and tight end Jake Tonges would miss significant time following a rash of Week 1 injuries, given San Francisco's history. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss the fallout from those recovery timelines. With Stribling sidelined 10 weeks and Tonges out for the rest of the season following their respective surgeries, do the 49ers have enough offensive depth to sustain their hot start as the Miami Dolphins visit Levi's Stadium in Week 2?

    --

    (0:00) De’Zhaun Stribling undergoes ankle surgery, out 10 weeks
    (3:00) Jake Tonges has season-ending knee surgery
    (8:00) Kaelon Black earns rare confidence from coaches as rookie
    (10:00) How 49ers intend to cover Stribling’s role
    (15:00) 49ers' offense impresses in Week 1
    (20:00) 49ers' defense was even more impressive
    (30:00) Looking ahead to home opener vs. Dolphins

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  • 49ers Talk: A San Francisco 49ers Podcast

    Who steps up for 49ers after De'Zhaun Stribling's injury?

    09/14/2026 | 38 mins.
    “49ers Talk” co-hosts Matt Maiocco and Jennifer Lee Chan recap San Francisco’s Week 1 win over the Los Angeles Rams and highlight key performances before looking ahead to the team's Week 2 matchup against the Miami Dolphins.
    --
    (2:05) How Rams weren’t physically prepared for Week 1
    (4:21) Breaking down NFC West standings after Week 1
    (7:20) De’Zhaun Stribling out at least one month with ankle injury
    (9:00) How 49ers receivers fared vs. Rams without Stribling
    (13:48) Kaelon Black produces strong Week 1 performance
    (19:35) What starting two rookies vs. Rams means for 49ers
    (23:02) Why 49ers' offensive line is strength this season
    (33:31) Looking ahead to Week 2 vs. Dolphins

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About 49ers Talk: A San Francisco 49ers Podcast
NBC Sports Bay Area 49ers insider Matt Maiocco and reporter Jennifer Lee Chan bring you comprehensive NFL coverage of all things San Francisco 49ers. Don't miss weekly in-depth interviews with players, coaches, front-office personnel, alumni and fellow media members. Check out all new episodes year-round.
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