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Rapid Response RN

Sarah Lorenzini
Latest episode

173 episodes

  • Rapid Response RN

    168: Thyroid Storm: When the Body Ramps Up Into Overdrive

    11/06/2026 | 45 mins.
    One septic patient, heart rate of 164, and blood pressure that doesn’t fit… Let’s break down what really happens during thyroid storm.
    Sarah shares the case of a 26-week pregnant woman admitted with urosepsis, who suddenly becomes flushed, sweaty and confused with vital signs that aren’t exactly fitting the sepsis clinical picture. From the clues that show up during the bedside assessment to compounding conditions, she shares how a diagnosis was reached and how multiple teams came together to treat the patient.
    You’ll learn why hyperthyroidism can become thyroid storm, the red flags to watch for, and the treatment approach that targets the storm without doing more harm.
    Topics discussed in this episode:
    Bedside assessment clues you can’t get from the chart
    Why sinus tachycardia is a symptom, not a diagnosis
    Severe-range blood pressure and preeclampsia in pregnancy
    Thyroid physiology and Graves’ disease
    Common triggers of thyroid storm
    How thyroid storm affects the heart, the metabolic system, and brain
    Diagnosing thyroid storm: labs and the Burch-Wartofsky Point Scale
    Choosing the right beta blocker
    Why iodine timing matters in treatment
    The art of nursing when a diagnosis doesn’t explain everything

    The 2026 joint consensus statement on management of thyroid storm, published in the European Thyroid Journal:
    https://doi.org/10.1530/ETJ-26-0043
    The American Thyroid Association’s 2026 Guidelines for Thyroid Disease in Preconception, Pregnancy, and Postpartum:
    https://journals.sagepub.com/doi/10.1177/10507256261445624
    ACOG District IV’s review of Hypertensive Disorders of Pregnancy:
    https://www.acog.org/community/districts-and-sections/district-iv/whats-new/countdown-to-intern-year-week-3-hypertensive-disorders

    Mentioned in this episode:
    CONNECT
    📸 Connect on Instagram: https://www.instagram.com/therapidresponsern/

    📚 Check out my course: https://www.rapidresponseandrescue.com/learnmore

    🧑‍💻Check out my website: https://www.rapidresponseandrescue.com/

    📬 Subscribe to my newsletter: https://www.rapidresponseandrescue.com/login

    🎁 Affiliation and discounts: https://www.rapidresponseandrescue.com/therapidresponsern

    ✅ Earn CE’s for listening to podcasts through RNegade: https://rnegade.thinkific.com/?ref=d9d541


    SAY THANKS
    💜Leave a review on Apple Podcasts: https://podcasts.apple.com/ca/podcast/rapid-response-rn/id1535997752

    💚Leave a rating on Spotify: https://open.spotify.com/show/55LQqeDg6XFeixvZLEp4xE


    ⏱️ To get the FREE Rapid Response RN Assessment Guide and the coupon code for $10 off the cost of the course, message Sarah on Instagram @TheRapidResponseRN and type the word PODCAST!

    This episode was produced by Podcast Boutique https://www.podcastboutique.com



    Eko CORE 300
    Check out the new Eko CORE 300 Digital Stethoscope here:
    https://www.ekohealth.com/products/core-300-digital-stethoscope?srsltid=AYCX9vJR2a5qzFJvkovW0DQ-H6ZExUlDTwRFjrl_S4dzz_IQztyYX99m
  • Rapid Response RN

    167: When a Stroke Doesn't Look Like a Stroke: Recognizing Basilar Artery Occlusions

    10/24/2026 | 46 mins.
    How do you recognize a stroke when the usual symptoms are present? No facial droop. No slurred speech. No one-sided weakness.
    In this episode, you'll hear the case of a post-op patient with normal vital signs but complaints of double vision. What follows is one of the most devastating types of ischemic stroke: a basilar artery occlusion.
    Sarah walks through each decision that led to the patient's full recovery, from the bedside nurse's decision to activate the rapid response team, the the RRT nurse calling a stroke alert, to thrombectomy when thrombolytics weren’t an option. She also breaks down when common symptoms like dizziness should raise concern for basilar artery occlusion, why strokes like this one are so easy to miss with your typical FAST exam alone, and how a tour of the brain helps you predict neurological deficits.
    Topics discussed in this episode:
    Why the nurse called rapid response for a post-op patient
    Anterior vs. posterior circulation
    Classic vs. atypical presentations of basilar artery occlusion
    Why FAST alone can miss posterior circulation strokes
    Locked-in syndrome and assessing consciousness
    Stroke localization: a tour of the brain
    IV thrombolytics: alteplase, tenecteplase, and bleeding risk
    When to use mechanical thrombectomy
    CT perfusion: core infarct vs. ischemic penumbra
    5 important takeaways for your next neuro emergency

    The American Heart Association/American Stroke Association's 2026 Guideline for the Early Management of Patients With Acute Ischemic Stroke:
    https://www.ahajournals.org/doi/10.1161/STR.0000000000000513
    Mentioned in this episode:
    Eko CORE 300
    Check out the new Eko CORE 300 Digital Stethoscope here:
    https://www.ekohealth.com/products/core-300-digital-stethoscope?srsltid=AYCX9vJR2a5qzFJvkovW0DQ-H6ZExUlDTwRFjrl_S4dzz_IQztyYX99m
  • Rapid Response RN

    166: When the Mitral Valve Breaks: Papillary Muscle Rupture After MI

    09/18/2026 | 44 mins.
    "I feel like I'm drowning." Four days after a STEMI, a patient who had been recovering well is sitting bolt upright, coughing up pink, frothy sputum, and unable to catch his breath.
    In this episode, Sarah walks you through a worst-case scenario complication every cardiac nurse needs on their radar: post-MI papillary muscle rupture causing acute, severe mitral regurgitation. This is one of those zebra diagnoses that you may never see... but if you do, recognizing it early is what gets your patient to the OR alive.
    Sarah breaks down the pathophysiology behind the patient's sudden deterioration, the clues that will help you catch a mechanical complication, and how to treat the patient — including which medications help (or backfire), and where BiPAP and mechanical support fit in.
    Topics discussed in this episode:
    Case presentation: sudden respiratory distress 4 days post-STEMI
    Mitral valve anatomy and the role of the papillary muscles
    Why mechanical complications happen days after an MI
    Acute vs. chronic mitral regurgitation
    Why the lungs flood while the organs starve
    Why murmurs can be misleading
    BiPAP and the risks of intubating a patient in shock
    Afterload reduction vs. norepinephrine
    When Lasix helps and when it doesn't
    Mechanical circulatory support: IABP, Impella, and VA-ECMO
    How to communicate with a frightened patient
  • Rapid Response RN

    165: Breaking the Storm Part 2: Antiarrhythmics, Sympathetic Blockade, and the Emerging Role of Esmolol

    07/15/2026 | 27 mins.
    The shock worked. The rhythm converted. And then V-fib came right back. Now what?
    Part two of this series explores the physiology and pharmacology driving recurrent V-fib so you can respond confidently when shocks aren’t enough.
    You'll learn how the body's sympathetic nervous system response keeps the heart unstable, why epinephrine can both help and hurt, when to reach for lidocaine over amiodarone, and what the research says about the emerging role of esmolol to target the storm itself (not just the arrhythmia).
    Topics discussed in this episode:
    The sympathetic nervous system and cardiac arrest
    Why epinephrine both helps and hurts
    Amiodarone vs. lidocaine: which is better?
    Key findings from the ROC-ALPS trial
    Why antiarrhythmics don't replace defibrillation
    The evidence behind esmolol in refractory V-fib
    3 lessons for codes when ACLS isn't enough
  • Rapid Response RN

    BONUS EPISODE: Rapid Response Calls That Never Should Have Happened from the Nurse Gwenny Podcast

    07/12/2026 | 43 mins.
    This special episode was recorded and released on the Nurse Gwenny Podcast. We talked about some of those early signs of deterioration that are often missed and how we can speak up and advocate before the patient crashes.
    Check out this episode and so many more over at the Nurse Gwenny Podcast
    And, you can join the Nurse Gwenny Library to earn CE credits for listening to the show!
    Use code: rapidresponsern
    to get a discount on your membership:
    https://library.nursegwenny.com/bundles/nurse-gwenny-library-membership
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About Rapid Response RN
Do you want to go from dreading emergencies to feeling confident and ready to jump into action to rescue your patient? Well, this show will let you see emergencies unfold through the eyes of a Rapid Response Nurse. With real life stories from the frontlines of nursing, host Sarah Lorenzini MSN, RN, CCRN, CEN, a Rapid Response Nurse and educator, shares her experiences at rapid response events and breaks down the pathophysiology, pharmacology, and the important role the nurse plays during emergencies. If you want to sharpen your assessment skills and learn how to think like a Rapid Response Nurse, then Sarah is here to share stories, tips, tricks, and mindsets that will prepare you to approach any emergency. Every episode is packed full of exactly what you need to know to handle whatever crisis that could arise on your shift. It’s one thing to get the right answer on the test, but knowing how to detect when YOUR patient is declining and what to do when YOUR patient is crashing is what will make or break your day… and might just save your patient’s life.
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