PodcastsEducationRapid Response RN

Rapid Response RN

Sarah Lorenzini
Rapid Response RN
Latest episode

159 episodes

  • Rapid Response RN

    154: Physiology-Guided Sepsis Resuscitation: ANDROMEDA-SHOCK 2, Dynamic Fluid Responsiveness, and SEP-1 with Guest Jaclyn Bond

    1/16/2026 | 47 mins.
    The science is finally catching up to what clinicians have long known: more fluids aren't always the answer to septic shock. In this episode, host Sarah Lorenzini and Jaclyn Bond MSN-LM, MBA-HM explain what the ANDROMEDA-SHOCK 2 trial reveals about physiology-guided sepsis resuscitation and why fixed-volume fluid strategies can lead to avoidable harm.
    They break down how dynamic fluid responsiveness testing helps teams stop guessing, and how tools like FloPatch support real-time assessment of carotid flow time and stroke volume. You'll leave with a clearer idea of when to give fluids, when to stop, and how to justify the decision.
    Topics discussed in this episode:
    The purpose and key findings of the ANDROMEDA-SHOCK 2 study
    Why dynamic measures of fluid responsiveness matter more than static vitals
    What recent meta-analysis data shows about physiology-guided fluid strategies
    Carotid flow time: what it is, how it’s measured, and how it guides decisions
    Hemodynamic assessment and bedside limitations
    How FloPatch supports real-time assessment so you can make individualized fluid decisions
    SEP-1 2026 guideline updates and why it’s better for patients
    How to apply these principles to your workflow

    Website: www.flosonicsmedical.com
    See FloPatch in action: https://hubs.ly/Q03-68Hg0
    Mentioned in this episode:
    CONNECT
    📸 Connect on Instagram: https://www.instagram.com/therapidresponsern/

    📚 Check out my course: https://www.rapidresponseandrescue.com/learnmore

    🧑‍💻Check out my website: https://www.rapidresponseandrescue.com/

    📬 Subscribe to my newsletter: https://www.rapidresponseandrescue.com/login

    🎁 Affiliation and discounts: https://www.rapidresponseandrescue.com/therapidresponsern

    ✅ Earn CE’s for listening to podcasts through RNegade: https://rnegade.thinkific.com/?ref=d9d541


    SAY THANKS
    💜Leave a review on Apple Podcasts: https://podcasts.apple.com/ca/podcast/rapid-response-rn/id1535997752

    💚Leave a rating on Spotify: https://open.spotify.com/show/55LQqeDg6XFeixvZLEp4xE


    ⏱️ To get the FREE Rapid Response RN Assessment Guide and the coupon code for $10 off the cost of the course, message Sarah on Instagram @TheRapidResponseRN and type the word PODCAST!

    This episode was produced by Podcast Boutique https://www.podcastboutique.com
  • Rapid Response RN

    153: Remix: Managing Crashing Pulmonary Embolism Patients

    1/02/2026 | 26 mins.
    Pulmonary embolisms don’t always announce themselves... sometimes they ambush.
    One minute your patient is walking with physical therapy, the next they’re hypotensive, hypoxic, and coding. This re-released early episode dives deep into why PE patients can look deceptively stable… right up until they aren’t.
    In this episode, I revisit one of my earliest case-based teachings on pulmonary embolism, updated with an added segment on vasopressin use in obstructive shock from PE. Through real bedside stories from my time as a rapid response and ER nurse, we break down the physiology behind PE-related collapse, why intubation isn’t always the answer, and how to think through management when the right ventricle is failing in front of you. This is a sobering but essential refresher on one of the most dangerous diagnoses we encounter.
    Topics discussed in this episode:
    Why pulmonary embolism is a common cause of in-hospital cardiac arrest (even if it’s not common overall)
    Classic and subtle PE presentations and why they’re often missed
    A real-time rapid response case: stable to crashing in minutes
    Risk factors for PE and the anticoagulation double-edged sword
    Obstructive shock explained: what’s actually killing the patient
    Right ventricular failure, septal bowing, and the spiral of death
    Why intubation can worsen outcomes in massive PE
    Vasopressors in PE: norepinephrine, epinephrine, and vasopressin
    The unique benefits of vasopressin in obstructive shock
    Thrombolysis vs. thrombectomy: when TPA helps — and when it’s deadly
    Bedside echo findings that point to massive PE
    Why PE patients can crash during transport (and what to always bring)
    Nursing vigilance, rapid escalation, and activating help early
    When perfect care still isn’t enough and the heart of nursing in end-of-life moments

    Mentioned in this episode:
    CONNECT
    📸 Connect on Instagram: https://www.instagram.com/therapidresponsern/

    📚 Check out my course: https://www.rapidresponseandrescue.com/learnmore

    🧑‍💻Check out my website: https://www.rapidresponseandrescue.com/

    📬 Subscribe to my newsletter: https://www.rapidresponseandrescue.com/login

    🎁 Affiliation and discounts: https://www.rapidresponseandrescue.com/therapidresponsern

    ✅ Earn CE’s for listening to podcasts through RNegade: https://rnegade.thinkific.com/?ref=d9d541


    SAY THANKS
    💜Leave a review on Apple Podcasts: https://podcasts.apple.com/ca/podcast/rapid-response-rn/id1535997752

    💚Leave a rating on Spotify: https://open.spotify.com/show/55LQqeDg6XFeixvZLEp4xE


    ⏱️ To get the FREE Rapid Response RN Assessment Guide and the coupon code for $10 off the cost of the course, message Sarah on Instagram @TheRapidResponseRN and type the word PODCAST!

    This episode was produced by Podcast Boutique https://www.podcastboutique.com...
  • Rapid Response RN

    152: "Don't Touch That Button!" Respiratory Wisdom, Myth Busting, and Everything Respiratory Therapists Wish Nurses Knew About Ventilation With Guest, Melody Bishop RT

    12/19/2025 | 55 mins.
    Some of the most common respiratory myths are still showing up at the bedside. But it's not your fault — most of us were never taught what an oxygenation problem versus a ventilation problem looks like in real time.
    In this episode, Melody Bishop RT explains how respiratory therapists think through oxygenation and ventilation to choose the right intervention and recognize when a patient is ready to breathe on their own. We’re calling out the old dogma and myths that can delay treatment and worsen patient outcomes!
    Topics discussed in this episode:
    Ventilation vs. oxygenation: the core building blocks
    V/Q mismatch explained
    ABG findings for low-flow vs. high-flow vs. BiPAP
    When CO₂ is the problem and the benefits of BiPAP
    Key indicators it’s time to intubate and the dangers of waiting
    The myth of resting patients on ventilation
    How to accurately assess spontaneous breathing trials
    COPD, oxygen, and the hypoxic drive myth
    What nurses should know about working with RTs

    Connect with Melody:
    https://melodybishoprt.com/
    Mentioned in this episode:
    Xshears are the best shears
    check em out here:
    https://xshear.com//discount/Rapid10

    and you can use code RAPID10 to get 10% off your purchase
    AND
    If you are planning to sit for your CCRN and would like to take the Critical Care Academy CCRN prep course you can visit https://www.ccrnacademy.com and use coupon code RAPID10 to get 10% off the cost of the course!
    CONNECT
    📸 Connect on Instagram: https://www.instagram.com/therapidresponsern/

    📚 Check out my course: https://www.rapidresponseandrescue.com/learnmore

    🧑‍💻Check out my website: https://www.rapidresponseandrescue.com/

    📬 Subscribe to my newsletter: https://www.rapidresponseandrescue.com/login

    🎁 Affiliation and discounts: https://www.rapidresponseandrescue.com/therapidresponsern

    ✅ Earn CE’s for listening to podcasts through RNegade: https://rnegade.thinkific.com/?ref=d9d541


    SAY THANKS
    💜Leave a review on Apple Podcasts: https://podcasts.apple.com/ca/podcast/rapid-response-rn/id1535997752

    💚Leave a rating on Spotify: https://open.spotify.com/show/55LQqeDg6XFeixvZLEp4xE


    ⏱️ To get the FREE Rapid Response RN Assessment Guide and the coupon code for $10 off the cost of the course, message Sarah on Instagram @TheRapidResponseRN and type the word PODCAST!

    This episode was produced by Podcast Boutique https://www.podcastboutique.com
  • Rapid Response RN

    151: Caring Close to Home: How Point-of-Care EEG and Community Innovation Are Changing ICU Care

    12/05/2025 | 30 mins.
    Rural nursing is anything but simple. They have limited resources, fewer specialists, and often have to send patients hours away from their families for a higher level of care. But all that is changing as new tech like Zeto brings monitoring right to the bedside and keeps more patients close to home.
    In this episode, ICU nurse leader Kristen RN shares how point-of-care EEG has empowered her team to catch subclinical seizures sooner and make faster, more informed clinical decisions. From buy-in to implementation, you'll hear how she advocated for her community and successfully integrated this technology into a small ICU. If you work in a rural or resource-limited facility, don't miss this one!

    Topics discussed in this episode:

    The unique challenges rural nurses and hospitals face
    Why keeping patients close to home matters
    How telemedicine and new tech are transforming rural healthcare
    Why subclinical seizures are hard to recognize
    How Zeto’s spot EEG helps nurses keep more patients close to home
    The positive impact on team confidence and patient care
    How you can advocate for the tools your community needs

    Learn more about Zeto here:
    https://zeto-inc.com/

    Mentioned in this episode:
    CONNECT
    📸 Connect on Instagram: https://www.instagram.com/therapidresponsern/

    📚 Check out my course: https://www.rapidresponseandrescue.com/learnmore

    🧑‍💻Check out my website: https://www.rapidresponseandrescue.com/

    📬 Subscribe to my newsletter: https://www.rapidresponseandrescue.com/login

    🎁 Affiliation and discounts: https://www.rapidresponseandrescue.com/therapidresponsern

    ✅ Earn CE’s for listening to podcasts through RNegade: https://rnegade.thinkific.com/?ref=d9d541


    SAY THANKS
    💜Leave a review on Apple Podcasts: https://podcasts.apple.com/ca/podcast/rapid-response-rn/id1535997752

    💚Leave a rating on Spotify: https://open.spotify.com/show/55LQqeDg6XFeixvZLEp4xE


    ⏱️ To get the FREE Rapid Response RN Assessment Guide and the coupon code for $10 off the cost of the course, message Sarah on Instagram @TheRapidResponseRN and type the word PODCAST!

    This episode was produced by Podcast Boutique https://www.podcastboutique.com
  • Rapid Response RN

    150: Sepsis-Induced Cardiomyopathy with Dr. Mahmoud Ibrahim MD

    11/21/2025 | 48 mins.
    Your pneumonia patient is hypotensive, tachycardic, and not responding to fluids… what did you miss? It could be sepsis-induced cardiomyopathy, a common under-recognized shock state you could see at the bedside.
    In this episode, Dr. Mahmoud Ibrahim MD and host Sarah Lorenzini use a case study to highlight how nurses, intensivists and the ICU team can work together to recognize the signs of sepsis-induced cardiomyopathy early and give patients a better chance at recovery. You'll learn the diagnostic clues that your patient’s heart is in trouble, how to approach controversial treatments like sodium bicarb, and what has to happen before intubation in a dual shock state.

    Topics discussed in this episode:

    What the initial bedside assessment says about the patient
    Treatment priorities for the  intensivist and nurse
    Signs that point to more than just sepsis
    Why fluids aren’t always the answer
    Blood pressure management: vasopressors and inotropes
    Pathophysiology of sepsis-induced cardiomyopathy
    How a sepsis-induced cardiomyopathy diagnosis changes treatment
    The vasopressin debate for sepsis-induced cardiomyopathy
    Clues your intervention isn’t working and what to do next
    How to prepare the patient for high-risk intubation
    What you need to know about administering sodium bicarb
    Why collaboration matters at every step for patient recovery

    Connect with Dr. Ibrahim:

    Instagram: https://www.instagram.com/icuboy_meded/
    Facebook: https://www.facebook.com/share/1Dg1ZTyfsN/
    TikTok: https://www.tiktok.com/@icuboy_meded
    Threads: https://www.threads.com/@icuboy_meded
    X: https://x.com/icuboy_meded

    Learn more about the different phenotypes in sepsis induced cardiomyopathy:
    https://journal.chestnet.org/article/S0012-3692(25)05143-8/abstract

    Mentioned in this episode:
    CONNECT
    📸 Connect on Instagram: https://www.instagram.com/therapidresponsern/

    📚 Check out my course: https://www.rapidresponseandrescue.com/learnmore

    🧑‍💻Check out my website: https://www.rapidresponseandrescue.com/

    📬 Subscribe to my newsletter: https://www.rapidresponseandrescue.com/login

    🎁 Affiliation and discounts: https://www.rapidresponseandrescue.com/therapidresponsern

    ✅ Earn CE’s for listening to podcasts through RNegade: https://rnegade.thinkific.com/?ref=d9d541


    SAY THANKS
    💜Leave a review on Apple Podcasts: https://podcasts.apple.com/ca/podcast/rapid-response-rn/id1535997752

    💚Leave a rating on Spotify: https://open.spotify.com/show/55LQqeDg6XFeixvZLEp4xE


    ⏱️ To get the FREE Rapid Response RN Assessment Guide and the coupon code for $10 off the cost of the course, message Sarah on Instagram @TheRapidResponseRN and type the word PODCAST!

    This episode was produced by Podcast Boutique https://www.podcastboutique.com



    Xshears are the best shears
    check em out here:
    https://xshear.com//discount/Rapid10

    and you can use code RAPID10 to get 10% off your purchase

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About Rapid Response RN

Do you want to go from dreading emergencies to feeling confident and ready to jump into action to rescue your patient? Well, this show will let you see emergencies unfold through the eyes of a Rapid Response Nurse. With real life stories from the frontlines of nursing, host Sarah Lorenzini MSN, RN, CCRN, CEN, a Rapid Response Nurse and educator, shares her experiences at rapid response events and breaks down the pathophysiology, pharmacology, and the important role the nurse plays during emergencies. If you want to sharpen your assessment skills and learn how to think like a Rapid Response Nurse, then Sarah is here to share stories, tips, tricks, and mindsets that will prepare you to approach any emergency. Every episode is packed full of exactly what you need to know to handle whatever crisis that could arise on your shift. It’s one thing to get the right answer on the test, but knowing how to detect when YOUR patient is declining and what to do when YOUR patient is crashing is what will make or break your day… and might just save your patient’s life.
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