Many of the longevity innovators in the Valley want to extend human life. But there are others who are trying to eliminate death. A lot of them. The tech billionaires who have never been told ‘no’ are driven to tackle the most insurmountable problems. They believe they can solve death by re-engineering the human in code. Problem is, it’s unlikely to happen in their natural lifetime. But technology is on their side. Every year, computing power doubles. Once a decade, the amount of change produces a whole new paradigm. And that is what they’re banking on. Science, combined with the rapid acceleration of technological change will keep them alive decade on decade until such time as they can achieve ‘longevity escape velocity’ - eternal life. In this series, technology reporter and psychologist Aleks Krotoski explores the frontiers of the extreme longevity pioneers. They've made their money in Silicon Valley. And with their technology solutions - PayPal, Facebook, cryptocurrencies - they've ushered in the world that we live in today, with all its unintended consequences. Some of them now want to solve the "problem" of aging, or even death, and they are making bigger strides than we may think. Can they? Should they? A Pillowfort production for BBC Radio 4 New episodes released Mondays. If you're in the UK, listen to the full series of Intrigue: The Immortals first on BBC Sounds: bbc.in/3WEQS5W

Loyal for Dogs is one of the companies in the longevity industry doing serious science. They are well-founded, have a killer team, and a very clear mission: to be the first to get a drug that treats ageing - not just the diseases of ageing, but ageing itself - to pass the rigorous Food and Drug Administration approval process. Their CEO, Celine Halioua, is a maverick founder whose life has been guided by her ability to work systems. So, to meet her mission, she’s got a hack that will get her new ageing drug into trials. That will be a first for the longevity community, and the foundation stone for the next phase of our search for eternal life. In this series, technology reporter and psychologist Aleks Krotoski explores the frontiers of the extreme longevity pioneers. They've made their money in Silicon Valley. And with their technology solutions - PayPal, Facebook, cryptocurrencies - they've ushered in the world that we live in today, with all its unintended consequences. Some of them now want to solve the "problem" of aging, or even death, and they are making bigger strides than we may think. Can they? Should they? A Pillowfort production for BBC Radio 4 New episodes released Mondays. If you're in the UK, listen to the full series of Intrigue: The Immortals first on BBC Sounds: bbc.in/3WEQS5W

Jesse Karmazin’s Ambrosia Plasma clinic promised the fountain of youth, two litres of young plasma at a time. For a fee, anyone could go to his treatment centre in the redwood forest outside Silicon Valley and receive an infusion. The results - according to Karmazin - were remarkable. Silicon Valley billionaires were rumoured to be queuing up for their young blood. The problem was, the scientists whose work in mice he claimed to be bringing to the people disagreed with what he was doing, and he never backed up his claims with data. A journalist stepped in to investigate, and what she found was Silicon Valley hype without any substance. In this series, technology reporter and psychologist Aleks Krotoski explores the frontiers of the extreme longevity pioneers. They've made their money in Silicon Valley. And with their technology solutions - PayPal, Facebook, cryptocurrencies - they've ushered in the world that we live in today, with all its unintended consequences. Some of them now want to solve the "problem" of aging, or even death, and they are making bigger strides than we may think. Can they? Should they? A Pillowfort production for BBC Radio 4 New episodes released Mondays. If you're in the UK, listen to the full series of Intrigue: The Immortals first on BBC Sounds: bbc.in/3WEQS5W

The Conboys’ experiment gave a young Harvard medical school graduate a big idea. But, there is a big gap between the experiments they did with mice in the lab, and pumping young blood into human beings. Still, he registered his company, Ambrosia Plasma, on the Food and Drug Administration clinical trials website and began an ambitious human research experiment. For $8,000 in cash, cheque or digital transfer, anyone over the age of 35 could receive two litres of blood plasma from 16-25 year olds in their veins. The outcomes were ambitious - physical rejuvenation, weight loss, reversal of dementia, and healthy looking skin. Does this fairy tale have a happy ending? In this series, technology reporter and psychologist Aleks Krotoski explores the frontiers of the extreme longevity pioneers. They've made their money in Silicon Valley. And with their technology solutions - PayPal, Facebook, cryptocurrencies - they've ushered in the world that we live in today, with all its unintended consequences. Some of them now want to solve the "problem" of aging, or even death, and they are making bigger strides than we may think. Can they? Should they? A Pillowfort production for BBC Radio 4 New episodes released Mondays. If you're in the UK, listen to the full series of Intrigue: The Immortals first on BBC Sounds: bbc.in/3WEQS5W

Mike and Irina Conboy are a couple of tie-dye clad scientists in the bio-engineering department at the University of Berkeley. When they started researching ageing more than 20 years ago at Stanford, the field was nothing more than a spin-off from geroscience - most of their time at the lab bench was spent documenting signs and signals that our bodies are reaching their ends. But in 2005, they published an article in Science that suggested there is hope for reversing ageing our tired old bodies. And the best bit of their study was that they proved there’s ample supply of the base material to do it - young blood. Using a revolutionary but ancient technique, their results re-ignited the millennia-old search for life everlasting. In this series, technology reporter and psychologist Aleks Krotoski explores the frontiers of the extreme longevity pioneers. They've made their money in Silicon Valley. And with their technology solutions - PayPal, Facebook, cryptocurrencies - they've ushered in the world that we live in today, with all its unintended consequences. Some of them now want to solve the "problem" of aging, or even death, and they are making bigger strides than we may think. Can they? Should they? A Pillowfort production for BBC Radio 4 New episodes released Mondays. If you're in the UK, listen to the full series of Intrigue: The Immortals first on BBC Sounds: bbc.in/3WEQS5W